Nature Communications - current - nature.com sci...
Acta Cirurgica BrasileiraResveratrol inhibits TNF-α-induced inflammation to protect against renal ischemia/reperfusion injury in diabetic ratsAbstract Purpose To examine effects of resveratrol on renal ischemia/ reperfusion injury (I/R) in a streptozotocin (STZ)-induced diabetic rat model. Methods Twenty-four male Sprague Dawley rats were treated with STZ injection for the development of diabetes, and divided into the following groups: Sham group, I/R group and Resveratrol group (n=8). Resveratrol...
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Latest Results for Current MicrobiologyTwin Peaks: Presenting the Antagonistic Molecular Interplay of Curcumin with LasR and LuxR Quorum Sensing PathwaysAbstract Quorum sensing in bacteria is a cell density-dependent phenomenon in which, a community of cells communicate with each other using signalling molecules belonging to various families of which N-acyl homoserine lactone (AHL) is one. AHL acts via ligand–receptor interaction where receptors of AHL differ from species to species, and possess...
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Immunopharmacology and ImmunotoxicologyDual role of sirtuin 1 in inflammatory bowel disease.Related Articles Dual role of sirtuin 1 in inflammatory bowel disease. Immunopharmacol Immunotoxicol. 2020 Jul 03;:1-22 Authors: Bansal K, Singh N, Jaggi AS Abstract Silent information regulator-1 (SIRT-1), is a member of the class III group of histone deacetylases and is collectively called sirtuins. There have been preclinical and clinical studies indicating the downregulation and decreased activity of...
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Dysphagia - RehabilitationDevelopment and validation of a new mealtime assessment tool (MAT) for patients with dysphagia: A cross sectional study.Related Articles Development and validation of a new mealtime assessment tool (MAT) for patients with dysphagia: A cross sectional study. Clin Ter. 2020 Jul-Aug;171(4):e346-e356 Authors: Rossi G, Galeoto G, Amitrano A, Berardi A, Tofani M, Celletti C, Camerota F Abstract PURPOSE: This study aimed to create a new quantitative and qualitative Mealtime Assessment...
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Technologies in Treatment of Head & NeckCotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts.Related Articles Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts. Cancers (Basel). 2020 Jun 29;12(7): Authors: Yang CY, Liu CR, Chang IY, OuYang CN, Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL, Tsai TL, Liu H, Tseng CP, Chang YS, Wu...
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International journal of basic and clinical endocrinologyEffects of denosumab as compared with parathyroidectomy regarding calcium, renal, and bone involvement in osteoporotic patients with primary hyperparathyroidismAbstract Purpose To evaluate the effects of denosumab (Dmb) on calcium, renal, and bone involvement in osteoporotic patients with primary hyperparathyroidism (PHPT) and compare with those who underwent a parathyroidectomy (PTX) procedure. Methods This retrospective, longitudinal study...
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Targeted Oncogene Therapy Before Surgery in Pediatric Patients With Advanced Invasive Thyroid Cancer at Initial Presentation: Is It Time for a Paradigm Shift?: Related ArticlesTargeted Oncogene Therapy Before Surgery in Pediatric Patients With Advanced Invasive Thyroid Cancer at Initial Presentation: Is It Time for a Paradigm Shift?JAMA Otolaryngol Head Neck Surg. 2020 Jul 02;:Authors: Kazahaya K, Prickett KK, Paulson VA, Dahl JP, Manning SC, Rudzinski ER, Rastatter JC, Parikh SR, Hawkins DS, Brose...
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ScienceDirect Publication: Annals of Allergy, Asthma & ImmunologyDecreased nasal polyp eosinophils but increased mast cells in an AERD patient treated with reslizumab.Publication date: Available online 4 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Anna G. Staudacher, Anju T. Peters, Roderick G. Carter, Kevin C. Welch, Whitney W. StevensScienceDirect Publication: Annals of Allergy, Asthma & ImmunologySat Jul 04, 2020 16:10Clinical Use Of Biologics For Asthma Treatment...
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Single, high-dose local injection of bFGF improves thyroarytenoid muscle atrophy after paralysis.: Related ArticlesSingle, high-dose local injection of bFGF improves thyroarytenoid muscle atrophy after paralysis.Laryngoscope. 2020 01;130(1):159-165Authors: Goto T, Ueha R, Sato T, Fujimaki Y, Nito T, Yamasoba TAbstract OBJECTIVES/HYPOTHESIS: Unilateral vocal fold paralysis (UVFP) induces hoarseness due to progressive atrophy of the denervated thyroarytenoid (TA) muscle. Therefore, treatments...
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The Journal of laryngology and otology http://goo.gl/Tl02xDSimultaneous cochlear implantation and removal of acoustic neuroma: implications for hearing.Related Articles Simultaneous cochlear implantation and removal of acoustic neuroma: implications for hearing. J Laryngol Otol. 2020 Jun 17;:1-7 Authors: Roberts S, Levin B, Sanli H, Ferch R, Kong K, Eisenberg R Abstract OBJECTIVE: To present our data evaluating the feasibility of simultaneous cochlear implantation with resection of acoustic neuroma....
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cortical auditoryAuditory attention alterations in migraine: A behavioral and MEG/EEG study.Related Articles Auditory attention alterations in migraine: A behavioral and MEG/EEG study. Clin Neurophysiol. 2020 Jun 18;131(8):1933-1946 Authors: Masson R, Lévêque Y, Demarquay G, ElShafei H, Fornoni L, Lecaignard F, Morlet D, Bidet-Caulet A, Caclin A Abstract OBJECTIVES: To evaluate alterations of top-down and/or bottom-up attention in migraine and their cortical underpinnings. METHODS: 19 migraineurs...
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Oral and Maxillofacial SurgeryCan four-dimensional computed tomography support diagnosis and treatment planning?: a case report before and after coronoidectomyAbstract Introduction Elongated mandibular coronoid process is a rare condition defined as enlargement of the coronoid process. The only useful way to treat the mouth-opening limitation is resection of the elongated coronoid process. Four-dimensional CT (4DCT; three spatial dimensions plus time axis) is a novel imaging technique. Its usefulness...
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Indian Journal of Nuclear MedicinePreparedness of nuclear medicine departments during the severe acute respiratory syndrome-Coronavirus-2 (COVID-19) pandemicHarmandeep SinghIndian Journal of Nuclear Medicine 2020 35(3):194-196Indian Journal of Nuclear MedicineWed Jul 01, 2020 00:00Complete pathological response noted in explanted liver after Y90-SIR-Spheres therapy for hepatocellular carcinomaPiyush Chandra, Satish Nath, Deepti JainIndian Journal of Nuclear Medicine 2020 35(3):267-268 In the treatment...
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PsychophysiologyFeatures of autonomic cardiovascular control during cognition in major depressive disorderAbstract Previous research has suggested reduced parasympathetic cardiac regulation during cognitive activity in major depressive disorder (MDD). However, little is known about possible abnormalities in sympathetic control and cardiovascular reactivity. This study aimed to provide a comprehensive analysis of autonomic cardiovascular control in the context of executive functions in MDD. Thirty...
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The Journal of PhysiologyInhibitory control of active expiration by the Bötzinger complex in ratsKey points Contraction of abdominal muscles at the end of expiration during metabolic challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The emergence of this active expiratory pattern requires the recruitment of the expiratory oscillator located on the ventral surface of the medulla oblongata. Here, we show that an inhibitory circuitry located in the Bötzinger complex is an...
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Oral DiseasesOsteomyelitis, osteoradionecrosis, or medication‐related osteonecrosis of the jaws? Can CBCT enhance radiographic diagnosis?Abstract Objective To attempt defining differential radiographic diagnostic characteristics for osteonecrotic lesions using 2D as opposed to 3D images. Materials and Methods This was a cross‐sectional study. Subjects presenting mandibular ostenecrotic lesions (osteomyelitis, osteoradionecrosis and medication‐related osteonecrosis of the jaws) were selected and...
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ScienceDirect Publication: American Journal of Infection ControlStopping the Routine use of Contact Precautions for Management of MRSA and VRE at Three Academic Medical Centers: An Interrupted Time Series AnalysisPublication date: Available online 4 July 2020Source: American Journal of Infection ControlAuthor(s): Sarah Haessler, Elise M Martin, Mary Ellen Scales, Le Kang, Michelle Doll, Michael P. Stevens, Daniel Z. Uslan, Rachel Pryor, Michael B. Edmond, Emily Godbout, Salma Abbas, Gonzalo BearmanScienceDirect...
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The Journal of Prosthetic DentistryEffect of different fabrication techniques on the marginal precision of polyetheretherketone single-crown copingsPublication date: Available online 4 July 2020Source: The Journal of Prosthetic DentistryAuthor(s): Mazen A. Attia, Tamer E. ShokryThe Journal of Prosthetic DentistrySun Jul 05, 2020 15:54Physical and surface properties of a 3D-printed composite resin for a digital workflowPublication date: Available online 4 July 2020Source: The Journal of Prosthetic...
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bioRxiv Subject Collection: Evolutionary BiologyWolbachia and host intrinsic reproductive barriers contribute additively to post-mating isolation in spider mites [NEW RESULTS]Wolbachia are widespread maternally-inherited bacteria, suggested to play a role in arthropod host speciation through induction of cytoplasmic incompatibility, but this hypothesis remains controversial. However, most studies focus on closely-related populations of single species, failing to consider the variable degrees of...
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Biomedicine & Pharmacotherapyβ-adrenergic activation may promote myosin light chain kinase degradation through calpain in pressure overload-induced cardiac hypertrophy: β-adrenergic activation results in MLCK degradationPublication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Shun Wang, Haixiong Wang, Xiaoling Su, Beilei Liu, Le Wang, Hui Yan, Shuai Mao, He Huang, Congxin Huang, Mian Cheng, Gang WuBiomedicine & PharmacotherapySun Jul 05, 2020 19:44Huoxuezhitong...
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Nature Communications - current - nature.com science feedsThe RNA quality control pathway nonsense-mediated mRNA decay targets cellular and viral RNAs to restrict KSHVNature Communications, Published online: 03 July 2020; doi:10.1038/s41467-020-17151-2Cellular nonsense-mediated mRNA decay (NMD) has been shown to play a role in defense against RNA viruses. Here, Zhao et al. show that NMD restricts the DNA virus Kaposi sarcoma-associated herpesvirus (KSHV) via targeting both cellular and viral transcripts...
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Intrinsic Laryngeal Lipoma Treated with Transoral CO₂ Laser Microsurgery: An Unusual Case Report.Related Articles Intrinsic Laryngeal Lipoma Treated with Transoral CO₂ Laser Microsurgery: An Unusual Case Report. Am J Case Rep. 2020 Jul 03;21:e920528 Authors: Lombardo N, Lobello N, Piazzetta G, Ciriolo M, Pelaia C, Testa D, Motta G Abstract BACKGROUND Lipomas, the most common soft tissue tumors, represent almost half of all benign mesenchymal neoplasms and are characterized by the absence of symptoms....
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Effective Response of Intrahepatic Cholangiocarcinoma to Pembrolizumab: A Case ReportBackground/Aim: The efficacy of pembrolizumab for intrahepatic cholangiocellular carcinoma (IHCCC) is not widely reported. Case Report: We began pembrolizumab treatment in a 69-year-old male with recurrent IHCCC at 18 months after his surgery because of the proven microsatellite instability (MSI)-high status. The patient had partial response, with an 82.5% reduction at the end of 18 courses. Immunostaining of the...
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Annals of NeurologyOptic disc classification by deep learning versus expert neuro‐ophthalmologistsAbstract Objective To compare the diagnostic performance of an artificial intelligence deep learning system with that of expert neuro‐ophthalmologists in classifying optic disc appearance. Methods The deep learning system was previously trained and validated on 14,341 ocular fundus photographs from 19 international centers. The performance of the system was evaluated on 800 new fundus photographs (400...
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European Archives of Oto-Rhino-LaryngologyPersonal protective equipment for ENT activity during COVID-19 pandemicAbstract Background In the COVID-19 era physicians have to face with need to perform office procedures maintaining the maximum safety for both the patient and the Doctor himself. The purpose of this paper was to suggest some equipment useful to perform outpatient visits in an ENT setting. Methods A simple modification of the standard headlight used during...European Archives of Oto-Rhino-LaryngologyFri...
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European Archives of Oto-Rhino-LaryngologyGustatory dysfunctions in COVID-19European Archives of Oto-Rhino-LaryngologySat Jul 04, 2020 08:22Chondrolaryngoplasty for transgender patients: feasibility of a scar-free approachAbstract Purpose Adult male-to-female transgender patients with a prominent thyroid notch can benefit from chondrolaryngoplasty with high satisfaction rates. It is a safe, effective, and established procedure with only minor and temporary complications. Until now, only external...
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Head and Neck[Expression and cellular provenance of interleukin 17A in non-eosinophilic chronic rhinosinusitis with nasal polyps].Related Articles [Expression and cellular provenance of interleukin 17A in non-eosinophilic chronic rhinosinusitis with nasal polyps]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jun 07;55(6):604-610 Authors: Chen XH, Chang LH, Huang JC, Li X, Lai XP, Wu XF, Huang ZZ, Wang ZY, Bao HW, Zhang GH Abstract Objective: To investigate the expression and cellular provenance...
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Head and NeckSimultaneous cochlear implantation and removal of acoustic neuroma: implications for hearing.Related Articles Simultaneous cochlear implantation and removal of acoustic neuroma: implications for hearing. J Laryngol Otol. 2020 Jun 17;:1-7 Authors: Roberts S, Levin B, Sanli H, Ferch R, Kong K, Eisenberg R Abstract OBJECTIVE: To present our data evaluating the feasibility of simultaneous cochlear implantation with resection of acoustic neuroma. METHODS: This paper describes a case series...
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Head and NeckDrain fluid amylase as a predictor of postoperative salivary fistula in cases with benign parotid tumours.Related Articles Drain fluid amylase as a predictor of postoperative salivary fistula in cases with benign parotid tumours. BMC Oral Health. 2020 Jul 02;20(1):184 Authors: Lu Y, Zhang S, Peng C, Yang W, Zhang C, Ren Z Abstract BACKGROUND: Late diagnosis of a salivary fistula increases the risk of wound infection and scarring. The purpose of the present study was to identify a quantitative...
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Head and NeckComparison of the Oral Steroids, Macrolides and Combination Therapy in Nasal Polyposis Patients.Related Articles Comparison of the Oral Steroids, Macrolides and Combination Therapy in Nasal Polyposis Patients. Sisli Etfal Hastan Tip Bul. 2020;54(2):211-217 Authors: Tetik F, Korkut AY, Kaya KS, Ucak I, Celebi I, Coskun BU Abstract Objectives: In this study, our aim was to compare oral steroid therapy with macrolide therapy and with oral steroid + macrolide (combine) therapy in patients...
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Head and NeckTransoral thyroidectomy (TOETVA): Complications, surgical time and learning curve.Related Articles Transoral thyroidectomy (TOETVA): Complications, surgical time and learning curve. Oral Oncol. 2020 Jun 30;110:104871 Authors: Lira RB, Ramos AT, Nogueira RMR, de Carvalho GB, Russell JO, Tufano RP, Kowalski LP Abstract BACKGROUND: Since 2018, transoral endoscopic thyroidectomy vestibular approach (TOETVA) has emerged as a true scarless thyroid surgery. In this study, we explore early...
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Alcohol and HomeostasisBiosynthesis pathway of indole-3-acetyl-myo-inositol during development of maize (Zea mays L.) seeds.Related Articles Biosynthesis pathway of indole-3-acetyl-myo-inositol during development of maize (Zea mays L.) seeds. J Plant Physiol. 2020 Feb;245:153082 Authors: Ostrowski M, Ciarkowska A, Dalka A, Wilmowicz E, Jakubowska A Abstract Indole-3-acetic acid (IAA) conjugation is one of the mechanisms responsible for auxin homeostasis. IAA ester conjugates biosynthesis has been...
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Oral and Maxillofacial SurgeryRe: Oral and maxillofacial surgery simulation: efficacy for medical studentsWe read with interest the study by Zargaran et al,1 evaluating a simulation course for medical students, designed to bridge the gap between theoretical oral and maxillofacial surgerical (OMFS) teaching and clinical practice. As medical students at the University of Cambridge, we are pleased to see that the current under-representation of OMFS at medical school is being tackled and wish to share...
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BioMed Research InternationalMultitarget Therapeutics for Neurodegenerative DiseasesBioMed Research International07:05The Postural Control Indexes during Unipodal Support in Patients with Idiopathic ScoliosisProper posture provides the best balance and body stability at minimal muscular effort. It is constantly controlled by the central nervous system, which integrates the stimuli from the proprioceptors (deep feeling sensors), vision receptors, and balance receptors through the subcortical structures....
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Pathogens, Vol. 9, Pages 536: Inactivation of Scrapie Prions by the Electrically Charged Disinfectant CAC-717Pathogens, Vol. 9, Pages 536: Inactivation of Scrapie Prions by the Electrically Charged Disinfectant CAC-717 Pathogens doi: 10.3390/pathogens9070536 Authors: Akikazu Sakudo Yoshifumi Iwamaru Koichi Furusaki Makoto Haritani Rumiko Onishi Morikazu Imamura Takashi Yokoyama Yasuhiro Yoshikawa Takashi Onodera Previous studies have revealed that the electrically charged disinfectant CAC-717 has...
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Journal of FungiJoF, Vol. 6, Pages 100: Lipid Species in the GI Tract are Increased by the Commensal Fungus Candida albicans and Decrease the Virulence of Clostridioides difficileJoF, Vol. 6, Pages 100: Lipid Species in the GI Tract are Increased by the Commensal Fungus Candida albicans and Decrease the Virulence of Clostridioides difficile Journal of Fungi doi: 10.3390/jof6030100 Authors: Jesus A. Romo Laura Markey Carol A. Kumamoto Prior antibiotic treatment is a risk factor for Clostridioides...
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Diversity, Vol. 12, Pages 266: Mating System in a Native Norway Spruce (Picea abies [L.] KARST.) Stand-Relatedness and Effective Pollen Population Size Show an Association with the Germination Percentage of Single Tree ProgeniesDiversity, Vol. 12, Pages 266: Mating System in a Native Norway Spruce (Picea abies [L.] KARST.) Stand-Relatedness and Effective Pollen Population Size Show an Association with the Germination Percentage of Single Tree Progenies Diversity doi: 10.3390/d12070266 Authors: Oliver...
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Antibiotics, Vol. 9, Pages 380: Current Concepts in Community and Ventilator Associated Lower Respiratory Tract Infections in ICU PatientsAntibiotics, Vol. 9, Pages 380: Current Concepts in Community and Ventilator Associated Lower Respiratory Tract Infections in ICU Patients Antibiotics doi: 10.3390/antibiotics9070380 Authors: Ignacio Martin-Loeches It is widely known that pneumonia (either community acquired or hospital acquired, as like ventilator associated pneumonia (VAP)), is the most frequent...
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