Cancers, Vol. 11, Pages 1420: Monoclonal Antibodies in Dermatooncology—State of the Art and Future PerspectivesCancers, Vol. 11, Pages 1420: Monoclonal Antibodies in Dermatooncology—State of the Art and Future Perspectives Cancers doi: 10.3390/cancers11101420 Authors: Malgorzata Bobrowicz Radoslaw Zagozdzon Joanna Domagala Roberta Vasconcelos-Berg Emmanuella Guenova Magdalena Winiarska Monoclonal antibodies (mAbs) targeting specific proteins are currently the most popular form of immunotherapy used...
Tue Sep 24, 2019 09:32
Molecular CarcinogenesisXRCC1‐mediated DNA repair is associated with progression‐free survival of multiple myeloma patients after autologous stem cell transplantAbstract Autologous stem cell transplant (ASCT) with high‐dose melphalan (HDM) is the standard treatment for fit multiple myeloma (MM) patients. It is generally believed that some DNA repair proteins impact the activity to repair melphalan‐induced DNA damage, thus potentially contributing to the patient's clinical response. However, knowledge...
Tue Sep 24, 2019 09:31
NeuroImageModality-general representations of valences perceived from visual and auditory modalitiesPublication date: December 2019Source: NeuroImage, Volume 203Author(s): Jin Gu, Linjing Cao, Baolin LiuAbstractValence is a dimension of emotion and can be either positive, negative, or neutral. Valences can be expressed through the visual and auditory modalities, and the valences of each modality can be conveyed by different types of stimuli (face, body, voice or music). This study focused on the...
Tue Sep 24, 2019 09:30
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-FacialRadix saw: a useful tool for rhinoplasty to correct high radix.Related ArticlesRadix saw: a useful tool for rhinoplasty to correct high radix. Braz J Otorhinolaryngol. 2019 Aug 07;: Authors: Şeneldir S, Dizdar D, Tuna A Abstract INTRODUCTION: The most difficult aspect of radix lowering is determining the maximum amount of bone that can be removed with osteotomes; here, we describe use of a radix saw, which is a new tool for determining...
Tue Sep 24, 2019 09:29
pubmed: health technologyHelicobacter p ylori eradication treatment for gastric carcinoma prevention in asymptomatic or dyspeptic adults: systematic review and Bayesian meta-analysis of randomised controlled trials.Related ArticlesHelicobacter p ylori eradication treatment for gastric carcinoma prevention in asymptomatic or dyspeptic adults: systematic review and Bayesian meta-analysis of randomised controlled trials. BMJ Open. 2019 Sep 20;9(9):e026002 Authors: Terasawa T, Hamashima C, Kato K, Miyashiro...
Tue Sep 24, 2019 09:29
Digestive EndoscopySystematic reviews and meta‐analysis in advanced endoscopy procedures: Not only numbersAbstract Systematic reviews and meta‐analysis are booming. Although they were initially thought to be powerful tools to synthetize data of randomized controlled trials (RCTs), they are more and more used in observational studies and retrospective series. Particularly, in advanced endoscopy techniques, the reader often has to stand up to poor meta‐analyses of few studies before well‐designed...
Tue Sep 24, 2019 09:28
BioEssaysDeubiquitinating Enzymes in Model Systems and Therapy: Redundancy and Compensation Have ImplicationsWhole genome duplication early in chordate evolution produced deubiquitinating enzyme genes that diverged in sequence and became partially subfunctionalized. In species where one gene is later lost or pseudogenized knockout of the remaining gene may generate obvious developmental phenotypes whereas compensation can mask phenotypes in species with two functional genes. Abstract The multiplicity...
Tue Sep 24, 2019 09:27
Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies...
Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosisThe original version of the article unfortunately contained a typo in the fourth author name. The author name was incorrectly listed as Rochelle Tixeria. The correct name should be Rochelle Tixeira. The original article has been corrected.http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=10495&channel-name=Apoptosis15hMark above section as read ScienceDirect...
Tue Sep 24, 2019 09:26
Clinical and translational oncologyDetection of novel mitochondrial mutations in cytochrome C oxidase subunit 1 (COX1) in patients with familial adenomatous polyposis (FAP)Abstract Background Familial adenomatous polyposis (FAP) is an Autosomal dominant inherited disorder and a rare form of colorectal cancer (CRC) that is characterized by the development of hundreds to thousands of adenomas in the rectum and colon. Mostly, cancers develop after the advent of the polyps. It appears in both sexes...
Tue Sep 24, 2019 09:25
Should we change how we treat mild asthma?- Jennifer Middleton, MD, MPHInhaled corticosteroids are a mainstay for treating asthma; typically, they are prescribed on a scheduled basis, though many patients struggle with adherence. Two new studies may offer an alternative to scheduled inhaled corticosteroid dosing for patients with mild asthma.As described in the "Top POEMS of 2018 Consistent with the Principles of the Choosing Wisely Campaign," these two randomized controlled trials compared the twice...
Tue Sep 24, 2019 09:24
Provider preference for payment method under a national health insurance scheme: A survey of health insurance-credentialed health care providers in Ghanaby Francis-Xavier Andoh-Adjei, Eric Nsiah-Boateng, Felix Ankomah Asante, Koos van der Velden, Ernst SpaanPLOS ONE Alerts: New Articles12hGIVE me your attention: Differentiating goal identification and goal execution components of the anti-saccade effectby Owen Myles, Ben Grafton, Patrick Clarke, Colin MacLeod The anti-saccade task is a commonly used...
Tue Sep 24, 2019 09:22
HER2-targeted therapies — a role beyond breast cancer Nature Reviews Clinical Oncology, Published...
HER2-targeted therapies — a role beyond breast cancerNature Reviews Clinical Oncology, Published online: 23 September 2019; doi:10.1038/s41571-019-0268-3HER2-targeted therapies have dramatically improved the outcomes in women with HER2-positive breast cancer. Furthermore, genetic sequencing studies have revealed HER2 alterations in a range of other cancers, including gastric cancer, colorectal cancer and non-small-cell lung cancer. In this Review the authors describe the available data on HER2-targeted...
Tue Sep 24, 2019 09:20
Happiness Studies Coping with Work Stressors and Paving the Way for Flow: Challenge and Hindrance...
Happiness StudiesCoping with Work Stressors and Paving the Way for Flow: Challenge and Hindrance Demands, Humor, and CynicismAbstract Although the concept of flow at work is increasingly receiving scholarly attention, knowledge about the interaction between challenge and hindrance stress demands in the context of flow is still lacking. Moreover, little is known about the stress-relieving capacity of coping mechanisms in connection to work-related flow. The aim of our study is to investigate whether...
Tue Sep 24, 2019 09:19
British Medical JournalAsylum seeker whose breast cancer treatment was delayed over eligibility has diedAn Ethiopian asylum seeker with advanced breast cancer who was denied treatment for several weeks amid confusion about whether she should be charged by the NHS has died at the age of 39.Kelemua...British Medical Journal10hLabour pledges free personal care for over 65s most in needThe Labour Party has pledged to introduce free personal care in England for the people aged over 65 who need it the...
Tue Sep 24, 2019 09:17
Can an AI algorithm fool radiologists?A type of artificial intelligence (AI) algorithm called a generative adversarial...Read more on AuntMinnieEurope.comRelated Reading: AI malware highlights imaging's security weaknesses Fake views: Generating image data for machine learning AI algorithm produces synthetic brain MR images BIR: How machine learning can cut false positives Neural networks read mammograms as well as radiologistsAuntMinnieEurope.com Headlines22hMark above section as read European Archives...
Tue Sep 24, 2019 09:15
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