Surgical and Radiologic AnatomyVariation of three-dimensional femoral bowing and its relation to physical status and bone mineral density: a study with CTAbstract Purpose Anatomically, the femoral bone shows sagittal and coronal bowing. Pronounced bowing would affect femoral implant surgery accuracy, but factors associated with degrees of three-dimensional (3D) femoral bowing have not yet been identified. This study measured 3D femoral bowing and examined the correlation between 3D femoral bowing...
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CancerPrognosis and modulation mechanisms of COMMD6 in human tumours based on expression profiling and comprehensive bioinformatics analysisBritish Journal of Cancer, Published online: 16 September 2019; doi:10.1038/s41416-019-0571-xPrognosis and modulation mechanisms of COMMD6 in human tumours based on expression profiling and comprehensive bioinformatics analysisCancer03:00Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with...
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European Journal of Surgical Oncology (EJSO)Poor compliance with perioperative chemotherapy for resectable gastric cancer and its impact on survivalPublication date: October 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 10Author(s): Margreet van Putten, Valery E.P.P. Lemmens, Hanneke W.M. van Laarhoven, Hans F.M. Pruijt, Grard A.P. Nieuwenhuijzen, Rob H.A. VerhoevenAbstractBackgroundIn several Western European countries it is recommended to treat gastric cancer patients with...
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Sleep MedicineAnthropometric measurements in community-dwelling older adults of Amerindian ancestry with obstructive sleep apnea. The Atahualpa ProjectPublication date: Available online 13 September 2019Source: Sleep MedicineAuthor(s): Oscar H. Del Brutto, Robertino M. Mera, Pablo R. CastilloSleep MedicineFri Sep 13, 2019 15:02No Changes in Gut Microbiota after Two-Week Sleep Extension in Chronically Sleep-Deprived IndividualsPublication date: Available online 13 September 2019Source: Sleep MedicineAuthor(s):...
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World NeurosurgeryIs contrast stasis after Pipeline embolization device deployment associated with higher aneurysm occlusion rates?Publication date: Available online 13 September 2019Source: World NeurosurgeryAuthor(s): Kunal Vakharia, Muhammad Waqas, Stephan A. Munich, Jaims Lim, Andrew Gong, Felix Chin, Kenneth V. Snyder, Adnan H. Siddiqui, Elad I. LevyAbstractObjectiveTo assess the association of degree of contrast stasis in intracranial aneurysms (IAs) immediately after Pipeline embolization...
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Cervical Myelopathy Presenting without Symptoms in the Upper Extremities: Incidence and Presenting CharacteristicsPublication date: Available online 9 September 2019Source: World NeurosurgeryAuthor(s): John K. Houten, Jordan Pasternack, Robert P. NortonAbstractBackgroundA preponderance of common signs and symptoms of cervical myelopathy (CM) manifest in the upper extremities and include hand numbness, hand clumsiness, and distal upper extremity weakness. Cervical myelopathy presenting without symptoms...
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pubmed: "bmc med educ"[jour]Patient-centred orientation of students from different healthcare disciplines, their understanding of the concept and factors influencing their development as patient-centred professionals: a mixed methods study.Related ArticlesPatient-centred orientation of students from different healthcare disciplines, their understanding of the concept and factors influencing their development as patient-centred professionals: a mixed methods study. BMC Med Educ. 2019 Sep 11;19(1):347...
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radiol anatReappraisal of the classical abdominal anatomical landmarks using in vivo computerized tomography imaging.Related ArticlesReappraisal of the classical abdominal anatomical landmarks using in vivo computerized tomography imaging. Surg Radiol Anat. 2019 Sep 11;: Authors: Goyal R, Aggarwal A, Gupta T, Gulati A, Jaggi S, Mirjalili SA, Sahni D Abstract INTRODUCTION: With expanding scope of interventions it becomes mandatory to have correct and evidence-based knowledge of surface anatomy of...
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European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-RhinoAnterolateral thigh free flap in reconstruction of lateral skull base defects after oncological resection.Related ArticlesAnterolateral thigh free flap in reconstruction of lateral skull base defects after oncological resection. Eur Arch Otorhinolaryngol. 2019 Sep 12;: Authors: Trojanowski P, Szymański M, Trojanowska A, Andrzejczak A, Szczepanek...
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European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-RhinoAnterolateral thigh free flap in reconstruction of lateral skull base defects after oncological resection.Related ArticlesAnterolateral thigh free flap in reconstruction of lateral skull base defects after oncological resection. Eur Arch Otorhinolaryngol. 2019 Sep 12;: Authors: Trojanowski P, Szymański M, Trojanowska A, Andrzejczak A, Szczepanek...
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pubmed: sleep apneaProspective Randomized Controlled Trial on the Efficacy of Continuous Positive Airway Pressure and Adaptive Servo-Ventilation in the Treatment of Chronic Complex Insomnia.Related ArticlesProspective Randomized Controlled Trial on the Efficacy of Continuous Positive Airway Pressure and Adaptive Servo-Ventilation in the Treatment of Chronic Complex Insomnia. EClinicalMedicine. 2019 Aug;13:57-73 Authors: Krakow B, McIver ND, Ulibarri VA, Krakow J, Schrader RM Abstract Background:...
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pubmed: epilepsy treatmentImpact of Hyperventilation and Sleep Deprivation Upon Visual Evoked Potentials in Patients with Epilepsy.Related ArticlesImpact of Hyperventilation and Sleep Deprivation Upon Visual Evoked Potentials in Patients with Epilepsy. Neurol India. 2019 Jul-Aug;67(4):1027-1032 Authors: Dziadkowiak E, Podemski R Abstract Objectives: The diagnosis of epilepsy can cause many problems, especially when the routine electrophysiological tests are inconclusive. The aim of the present study...
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OncologyIdentification of key modules and prognostic markers in adrenocortical carcinoma by weighted gene co-expression network analysis.Related ArticlesIdentification of key modules and prognostic markers in adrenocortical carcinoma by weighted gene co-expression network analysis. Oncol Lett. 2019 Oct;18(4):3673-3681 Authors: Zou Y, Jing L Abstract Adrenocortical carcinoma (ACC) is a rare and aggressive cancer with a high relapse rate and limited treatment options. Therefore, the identification...
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Head and NeckPatient safety analysis in radiation burden of head computed tomography imaging in 1,185 neurosurgical inpatients.Related ArticlesPatient safety analysis in radiation burden of head computed tomography imaging in 1,185 neurosurgical inpatients. World Neurosurg. 2019 Sep 11;: Authors: Sheppard JP, Duong C, Romiyo P, Azzam D, Alkhalid Y, Nguyen T, Babayan D, Lagman C, Sun MZ, Prashant GN, Beckett JS, Yang I Abstract OBJECTIVE: We performed a retrospective analysis in a cohort of 1,185...
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Head and NeckEthnic differences of children with foreign body aspiration: a need for preventive education.Related ArticlesEthnic differences of children with foreign body aspiration: a need for preventive education. Eur Arch Otorhinolaryngol. 2019 Sep 12;: Authors: Ronen O, Kanelo F, Shor D, Ashkar M, Kepten I Abstract INTRODUCTION: Only in 2005 was a product labeling law passed in Israel that requires food companies to mark a choking hazard. We wished to investigate the influence of the hazard...
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Head and NeckCutaneous manifestation of IgG4-related disease mimicking dermatitis artefacta.Related ArticlesCutaneous manifestation of IgG4-related disease mimicking dermatitis artefacta. Australas J Dermatol. 2019 Sep 11;: Authors: Ashoka Menon V, Tong E, Slape DRL, Phan TA, Chan RC Abstract Dermatitis artefacta is a self-inflicted cutaneous disease presenting as sharply delineated ulcers, usually in accessible sites such as the head and neck. IgG4-related disease (IgG4-RD) is a recently recognised...
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Rare CancersIsolated hypoglossal nerve palsy due to a jugular foramen schwannoma.Related ArticlesIsolated hypoglossal nerve palsy due to a jugular foramen schwannoma. Ideggyogy Sz. 2019 Jul 30;72(7-8):282-284 Authors: Öztop-Çakmak Ö, Vanli-Yavuz E, Aygün S, Bastan B, Egemen E, Solaroğlu I, Gursoy-Ozdemir Y Abstract Introduction - Although the involvement of the hypoglossal nerve together with other cranial nerves is common in several pathological conditions of the brain, particularly the brainstem,...
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Rare CancersTreatment at low-volume hospitals is associated with reduced short-term and long-term outcomes for patients with retroperitoneal sarcoma.Related ArticlesTreatment at low-volume hospitals is associated with reduced short-term and long-term outcomes for patients with retroperitoneal sarcoma. Cancer. 2018 12 01;124(23):4495-4503 Authors: Keung EZ, Chiang YJ, Cormier JN, Torres KE, Hunt KK, Feig BW, Roland CL Abstract BACKGROUND: Retroperitoneal sarcomas (RPS) are rare tumors for which complete...
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pubmed: cell cycle arrestMiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro.Related ArticlesMiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro. Cell Signal. 2018 Sep;49:95-104 Authors: Li R, Qiao M, Zhao X, Yan J, Wang X, Sun Q Abstract Psoriasis is a common immune-mediated chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation,...
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pubmed: "world neurosurg"[jo...Long-term outcomes of gamma knife radiosurgery for cystic vestibular schwannomas.Related ArticlesLong-term outcomes of gamma knife radiosurgery for cystic vestibular schwannomas. World Neurosurg. 2019 Sep 11;: Authors: Lim SH, Park CK, Park BJ, Lim YJ Abstract OBJECTIVE: Vestibular schwannomas (VS) can either be solid or contain variable amounts of cystic components. It is established that gamma knife radiosurgery (GKS) was an effective treatment modality for solid...
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Human homeostasisFGF23 at the crossroads of phosphate, iron economy and erythropoiesis.Related ArticlesFGF23 at the crossroads of phosphate, iron economy and erythropoiesis. Nat Rev Nephrol. 2019 Sep 13;: Authors: Edmonston D, Wolf M Abstract Fibroblast growth factor 23 (FGF23) was initially characterized as an important regulator of phosphate and calcium homeostasis. New research advances demonstrate that FGF23 is also linked to iron economy, inflammation and erythropoiesis. These advances have...
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American Academy of AudiologyPreimplant Hearing Aid Fittings and Aided Audibility for Pediatric Cochlear Implant RecipientsAmerican Academy of AudiologySun Sep 15, 2019 05:28The Effect of Varying Test Administration and Scoring Procedures on Three Tests of (Central) Auditory Processing DisorderAmerican Academy of AudiologySun Sep 15, 2019 05:28Large Vestibular Aqueduct Syndrome: Parents' and Audiologists' PerspectivesAmerican Academy of AudiologySun Sep 15, 2019 05:28Measurement of Thresholds Using...
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Hellenic Anticancer InstitutePrediction of Portal Vein Thrombosis Following Hepatectomy for Perihilar Cholangiocarcinoma: Efficacy of Postoperative Portal Vein Diameter Ratio and AngleBackground: Portal vein thrombosis (PVT) is a life-threatening complication after hepatectomy. However, the relationship between postoperative PVT and morphometric features of the PV has not been fully elucidated yet. Patients and Methods: A total of 81 patients who underwent hepatectomy for perihilar cholangio-carcinoma...
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Hellenic Anticancer InstituteClinical Outcomes of Head and Neck Cancer Patients Who Undergo Resection, But Forgo Adjuvant TherapyBackground/Aim: This study aimed to evaluate the outcomes of patients with head and neck squamous cell carcinoma (HNSCC) who underwent resection and refused the recommended adjuvant therapy. Patients and Methods: Locoregional recurrence-free survival (LRRFS) and time to progression (TTP) were assessed in HNSCC patients treated with surgery who declined some or all adjuvant...
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Experimental DermatologyClinical, microbiological, immunological and imaging characteristics of tunnels and fistulas in hidradenitis suppurativa and Crohn's diseaseAbstract Hidradenitis suppurativa (HS) tunnels and Crohn's disease (CD) fistulas are a challenge to treat. Although pathogenic similarities have been described between HS and CD, recent studies indicate that clinical, microbiological, immunological and imaging characteristics differ between these diseases. This review highlights the differences...
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Child's Nervous SystemThe molecular oncology of bilateral high-grade thalamic astrocytomas in childrenAbstract Background Bilateral thalamic astrocytomas in children are exceedingly rare. These highly malignant tumors seldom respond to conventional treatment strategies and carry a grim prognosis for patients. However, recent advances in molecular oncology have had a positive impact on prognostication and treatment strategies of these tumors. Case-based review ...Latest Results for Child's Nervous...
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Pathology & Oncology ResearchFocal Adhesion Kinase (FAK) Overexpression and Phosphorylation in Oral Squamous Cell Carcinoma and their Clinicopathological SignificanceAbstract Focal adhesion kinase (FAK) is involved in progression of various cancers, and FAK overexpression has been associated with cancer invasion and metastasis. However, the involvement of FAK expression in the clinicopathological malignancy of oral squamous cell carcinoma (OSCC) remains unknown. In addition, there is no consensus...
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Future Oncology. Sarcoma patients' quality of life from diagnosis to yearly follow-up: experience...
Future Oncology.Sarcoma patients' quality of life from diagnosis to yearly follow-up: experience from an Italian tertiary care center.Related ArticlesSarcoma patients' quality of life from diagnosis to yearly follow-up: experience from an Italian tertiary care center. Future Oncol. 2019 Sep 12;: Authors: Maggi G, Terrenato I, Giacomelli L, Zoccali C, Condoleo MF, Falcicchio C, Baldi J, Vari S, Ferraresi V, Biagini R, Pugliese P Abstract Aim: To investigate sarcoma patients' perception of quality...
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Technologies in Treatment of Head & NeckMulti-institutional evaluation of knowledge-based planning performance of volumetric modulated arc therapy (VMAT) for head and neck cancer.Related ArticlesMulti-institutional evaluation of knowledge-based planning performance of volumetric modulated arc therapy (VMAT) for head and neck cancer. Phys Med. 2019 Aug;64:174-181 Authors: Kamima T, Ueda Y, Fukunaga JI, Shimizu Y, Tamura M, Ishikawa K, Monzen H Abstract PURPOSE: The aim of this study was to investigate...
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Clinical NeurophysiologyP1-04-04. Correlation between arterial spin labeling MRI and EEG in patients with non-convulsive status epilepticsPublication date: October 2019Source: Clinical Neurophysiology, Volume 130, Issue 10Author(s): Satoru Ohtomo, Hiroshi Otsubo, Hiroaki AraiClinical NeurophysiologySat Sep 14, 2019 13:07Mark above section as read The European Gastrointestinal Motility SocietyColonic mast cell numbers, symptom profile, and mucosal expression of elements of the epithelial barrier...
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Clinical NeurophysiologyP1-04-01. Questionnaire-based assessments of sleep problems in patients with epilepsyPublication date: October 2019Source: Clinical Neurophysiology, Volume 130, Issue 10Author(s): Mizuki Hara, Kazutaka Jin, Dai Agari, Yosuke Kakisaka, Takashi Miki, Nobukazu NakasatoClinical NeurophysiologySat Sep 14, 2019 13:07P2-24-01. Time from onset to EMG examination in ALS patients in Indonesia : A survey by ALS Indonesia foundationPublication date: October 2019Source: Clinical Neurophysiology,...
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Psycho-OncologyFeasibility and acceptability of using an Interactive Voice Response System (IVRS) to assess decision making about sun protectionAbstract Objective We developed an Interactive Voice Response System (IVRS), an automated telephone survey technology, to assess real‐time decision making about sun protection. We examined the feasibility and acceptability of IVRS in this electronic health (eHealth) context. Methods Melanoma patients who underwent surgery referred their first‐degree relatives...
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Anti-Cancer Drugs - Current IssueAntitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma modelsAs a novel orally active multitarget small molecule inhibitor, CS2164 has shown broad antitumor activities against several human tumor xenograft models in immune-compromised mice. However, the ability of CS2164 to modulate antitumor immunity in an immune-competent mouse tumor model remains undefined, although antiangiogenic treatment has been reported...
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Oral Pathology & MedicineThe efficacy and safety of thalidomide on the recurrence interval of continuous recurrent aphthous ulceration: a randomized controlled clinical trialAbstract Background Recurrent aphthous ulceration (RAU) is the most common oral mucosal disease. Some patients have almost continuous oral ulcers which influence the quality of life. The aim of this study was to observe the efficacy and safety of thalidomide on the recurrence interval of continuous RAU. Methods A randomized...
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The American Academy of Sleep MedicineAcute Drug-Induced Symptoms of Restless Legs Syndrome in an Emergency Department: What's in a Name?Stowe RC. Acute drug-induced symptoms of restless legs syndrome in an emergency department: what's in a name? J Clin Sleep Med. 2019;15(9):1381.The American Academy of Sleep MedicineSat Sep 14, 2019 00:57Autocycling During Noninvasive Positive Pressure Ventilation Producing a Prolonged Severe Apnea and Syncope, Further InsightsMu S, Howard ME, Hannan L. Autocycling...
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Clinical ImagingIncidental dedifferentiated mediastinal liposarcoma on F-18-fluciclovine PET/CTPublication date: Available online 13 September 2019Source: Clinical ImagingAuthor(s): Christine Boatright, Christopher M. Walker, Joseph Donald, Wei Cui, Alykhan S. NagjiAbstractFat-containing mediastinal masses, particularly mediastinal liposarcomas, are rare neoplasms that can grow to large sizes before becoming symptomatic and may be incidentally found on radiology examinations.In this case report,...
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Journal of Sleep ResearchReduced structural connectivity in Insomnia DisorderAbstract Insomnia Disorder is the most prevalent sleep disorder, and it involves both sleep difficulties and daytime complaints. The neural underpinnings of Insomnia Disorder are poorly understood. Several existing neuroimaging studies focused on local measures and specific regions of interests, which makes it difficult to judge their whole‐brain significance. We therefore here applied a data‐driven approach to assess differences...
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NeoplasiaRectal cancer sub-clones respond differentially to neoadjuvant therapyPublication date: October 2019Source: Neoplasia, Volume 21, Issue 10Author(s): Lynn M Frydrych, Peter Ulintz, Armand Bankhead, Christopher Sifuentes, Joel Greenson, Lillias Maguire, Regina Irwin, Eric R. Fearon, Karin M HardimanAbstractTreatment of locally advanced rectal cancer includes chemotherapy, radiation, and surgery but patient responses to neoadjuvant treatment are variable. We have shown that rectal tumors are...
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PeerJ Computer ScienceScreening and identification of SipC-interacting proteins in Salmonella enteritidis using Gal4 yeast two-hybrid system in duckThe zoonotic pathogen Salmonella not only reduces the production performance in ducks, but also poses a serious threat to human health through eggs and pollutes water bodies through feces. SipC, an effector protein of type III secretion systems (T3SS) in Salmonella, mediates translocation of effectors into the eukaryotic host. However, the precise role...
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Clinical Cancer Research current issueClinical Efficacy and Safety of Nivolumab: Results of a Multicenter, Open-label, Single-arm, Japanese Phase II study in Malignant Pleural Mesothelioma (MERIT)Purpose:Malignant pleural mesothelioma (MPM) is a rare and aggressive malignancy with poor prognosis. Patients with MPM who do not respond to standard first-line chemotherapy have limited treatment options. We evaluated the efficacy and safety of nivolumab, an immune checkpoint inhibitor, for the treatment...
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Diagnostic CytopathologyFine‐needle aspiration of the Warthin‐like variant of papillary thyroid carcinoma: A report of three casesAbstract In English literature, there are only few reports of Warthin‐like papillary thyroid carcinoma. We presented three cases and provided clinical, grossing, cytological, and histological correlation. In our point of view, the diagnosis of Warthin‐like papillary thyroid carcinoma is feasible based on cytomorphological aspects. Usually those cases present moderately...
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