Necrolytic migratory erythema (glucagonoma syndrome) associated with pancreatic neuroendocrine tumor presenting with superimposed cellulitis

Introduction: Necrolytic migratory erythema (NME) is a paraneoplastic dermatologic phenomenon classically associated with glucagon-producing tumors from the pancreatic alpha cells. It is characterized by an abnormally elevated blood level of glucagon and skin findings of NME in the setting of glucagon-secreting pancreatic neuroendocrine tumor. Erythematous scaly lesions with centrifugal growth commonly on perineum, distal extremities, lower abdomen, and face characterize the clinical appearance of the disease.