Commentary on: Outcomes of Acellular Dermal Matrix for Immediate Tissue Expander Reconstruction with Radiotherapy: A Retrospective Cohort Study

In this retrospective cohort study of women who underwent immediate tissue expander reconstruction at a major cancer center, the authors evaluated the effects of acellular dermal matrix (ADM) on patient outcomes in the setting of postmastectomy radiation therapy (PMRT).¹ Currently, 2-stage tissue expander/implant breast reconstruction is the most common type of reconstruction performed in the United States.² Meanwhile, increasing use of PMRT over the past decade has significantly impacted the clinical, aesthetic, and patient-reported outcomes of these procedures.^3-8 Despite the widespread adoption of ADM in implant-based breast reconstruction, there have been few well-designed studies assessing the benefits and risks of this material, particularly among women receiving PMRT. This study by Craig et al represents an important step forward in addressing this gap in our knowledge.