Combined treatment of striae using calcium hydroxylapatite, ascorbic acid delivered by microneedling, and microfocused ultrasound

Background and objective: Striae (i.e., stretch marks) are associated with the loss of collagen and reduced fibrillin and elastin in the skin. Currently available treatments are less than optimal. The objective of this retrospective study was to evaluate improvements in straie appearance after combined treatment with microneedling, topical ascorbic acid, calcium hydroxylapatite (CaHA; Merz North America), and microfocused ultrasound with visualization (MFU-V; Ulthera).