Reply to: “Prognostic significance of tumor budding in cutaneous squamous cell carcinoma”

To the Editor: We would like to thank Kanitakis and Karayannopoulou1 for highlighting that a key point of our article on the prognostic significance of tumor budding in cutaneous squamous cell carcinoma (cSCC) is the assessment method.2 We fully agree that a consensus method is needed because tumor budding is increasingly being recognized as a prognostic factor in several cancers.