Survivorship in Adults with Malignant Brain and other Central Nervous System Tumor from 2000-2014

Abstract

Background

The goal of this study was to provide up to date and comprehensive statistics on incidence, survival, and prevalence rates for selected malignant brain and other CNS tumors in adults.

Methods

The current study used CBTRUS data, provided by CDC, to examine incidence and SEER data to examine survival and prevalence in sixteen distinct malignant brain and other CNS histologies in adults (aged 20 years and older at diagnosis) from 2000-2014 overall and by sex, age group, race, and ethnicity.

Results

Glioblastoma had the highest incidence (4.40 per 100,000) and prevalence (9.23 per 100,000). Ependymal tumors had the highest 5- and 10-year relative survival (87.8% and 84.5%, respectively), while glioblastoma had the lowest 5- and 10-year relative survival (5.4% and 2.7%, respectively). Females generally had better survival and lower prevalence than males. Younger adults tended to have better survival than older adults, and prevalence varied greatly by age and histology. While survival did not vary significantly by race, White adults had higher prevalence than the other race groups. Hispanics generally had better survival rates and lower prevalence than non-Hispanics.

Conclusions

Survival varied greatly by age and ethnicity. Prevalence differed by sex, age, race, and ethnicity.