Cutaneous Features and Diagnosis of Primary Sjogren’s Syndrome: An Update and Review

SS is diagnostically challenging due to clinical and immunologic features which overlap with other connective tissue diseases, SS patients with cutaneous vasculitis, especially cryoglobulinemic vasculitis, have worse prognosis with increased risk of systemic vasculitis and lymphoma. SS patients with photosensitive annular erythema tend to have milder systemic and glandular involvement, Characteristic cutaneous features of SS are early diagnostic signs correlating with prognosis.