Proteins involved in the antioxidant and inflammatory response in rutin-treated human skin fibroblasts exposed to UVA or UVB irradiation

The proteome is the complete set of proteins expressed by an organism, including the post-translational modifications, is characteristic for cell type, its age, stage of differentiation and maturation, as well as environmental conditions [1]. The composition of this set of proteins is modified at any given time by various cell activities such as gene transcription and de novo biosynthesis of proteins, as well as by the degradation of old, damaged, inactive or just unnecessary molecules. At physiological conditions, the rate of protein synthesis and degradation should be balanced and adept to sustaining cell growth and function.