Removal of forearm lentigines in dyschromatosis universalis hereditaria with a 755-nm Q-switched alexandrite laser

Characterized by hyperpigmented and hypopigmented macules forming a reticulate pattern, dyschromatosis universalis hereditaria (DUH) was first described by Toyamo in Japan. Subsequent cases have been reported from other areas including Europe, China, Saudi Arabia, Tunisia, India, and Nigeria.1 A variable autosomal inheritance has been described, and a few sporadic cases have been reported. Spontaneous regression has not been recorded. Only one case involving treatment modality was reported in 2011.