Scleroderma is a chronic disease of unknown etiology characterized by skin fibrosis and is divided into two clinical entities: systemic sclerosis (SSc) and localized scleroderma (LSc, or morphea) [1]. SSc is a multisystem autoimmune and vascular disorder resulting in extensive tissue fibrosis of the skin and certain internal organs [2]. LSc differs from SSc in that it is not accompanied by Raynaud's phenomenon, acrosclerosis, and internal organ involvement, and is classified into 5 subtypes; circumscribed morphea, linear scleroderma, generalized morphea, pansclerotic morphea, and mixed morphea [3].
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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Σάββατο 16 Δεκεμβρίου 2017
Systemic sclerosis complicated with localized scleroderma-like lesions induced by Köbner phenomenon
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