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Τετάρτη 27 Σεπτεμβρίου 2017

Medicine by Alexandros G. Sfakianakis


Cancerology Oncology
Low viral load of Merkel cell polyomavirus in Iranian patients with head and neck squamous cell carcinoma: is it clinically important?
 
Abstract Recent studies show that the human Merkel cell polyomavirus (MCPyV) may be involved in causing cancer. The objective of this study was to assess the impact of MCPyV on the development of head and neck squamous cell carcinoma (HNSCC). Totally, 50 paraffin-embedded HNSCC biopsy samples and...
Cancerology Oncology
Hepatitis C Virus infections among clients attending an HIV testing and counseling center in Dhaka, Bangladesh
 
ABSTRACT The prevalence of hepatitis C virus (HCV) and genotypes among 965 individuals attending an HIV testing and counseling unit in Dhaka Bangladesh during Jan-Dec 2011 was determined. Anti-HCV antibody was detected in 4.4% individuals; the highest rate 37.8% was in people who inject drugs followed...
Cancerology Oncology
SIGNIFICANT IMPROVEMENT OF GLYCAEMIC CONTROL IN DIABETIC PATIENTS WITH HCV INFECTION RESPONDING TO DIRECT-ACTING ANTIVIRAL AGENTS
 
ABSTRACT AIM:Many studies showed insulin resistance amelioration in HCV-patients achieving Sustained Virologic Response (SVR) but results on glycaemic control in diabetic patients are unclear. This study aimed to assess fasting glucose (FG) and glycated haemoglobin (HbA1c) values before and after...
Cancerology Oncology
Long-term disability progression in primary progressive multiple sclerosis: a 15-year study
 
Abstract Prognostic markers of primary progressive multiple sclerosis evolution are needed. We investigated the added value of magnetic resonance imaging measures of brain and cervical cord damage in predicting long-term clinical worsening of primary progressive multiple sclerosis compared to simple...
Cancerology Oncology
Less is more: neural mechanisms underlying anomia treatment in chronic aphasic patients
 
Abstract Previous research with aphasic patients has shown that picture naming can be facilitated by concurrent phonemic cueing [e.g. initial phoneme(s) of the word that the patient is trying to retrieve], both as an immediate word retrieval technique, and when practiced repeatedly over time as a...
Cancerology Oncology
Clinical, pathological and functional characterization of riboflavin-responsive neuropathy
 
Abstract Brown-Vialetto-Van Laere syndrome represents a phenotypic spectrum of motor, sensory, and cranial nerve neuropathy, often with ataxia, optic atrophy and respiratory problems leading to ventilator-dependence. Loss-of-function mutations in two riboflavin transporter genes, SLC52A2 and SLC52A3,...
Cancerology Oncology
Divergent neural responses to narrative speech in disorders of consciousness
 
Abstract Objective Clinical assessment of auditory attention in patients with disorders of consciousness is often limited by motor impairment. Here, we employ intersubject correlations among electroencephalography responses to naturalistic speech in order to assay auditory attention among patients...
Cancerology Oncology
On the mechanisms of protein interactions: predicting their affinity from unbound tertiary structures
 
Abstract Motivation The characterization of the protein-protein association mechanisms is crucial to understanding how biological processes occur. It has been previously shown that the early formation of non-specific encounters enhances the realization of the stereospecific (i.e. native) complex...
Cancerology Oncology
DiversePathsJ: Diverse Shortest Paths for Bioimage Analysis
 
Abstract Motivation We introduce a formulation for the general task of finding diverse shortest paths between two end-points. Our approach is not linked to a specific biological problem and can be applied to a large variety of images thanks to its generic implementation as a user-friendly ImageJ/Fiji...
Cancerology Oncology
Canvas SPW: calling de novo copy number variants in pedigrees
 
Abstract Motivation Whole genome sequencing is becoming a diagnostics of choice for the identification of rare inherited and de novo copy number variants in families with various pediatric and late-onset genetic diseases. However, joint variant calling in pedigrees is hampered by the complexity of...
Cancerology Oncology
The systematic analysis of ultraconserved genomic regions in the budding yeast
 
Abstract Motivation In the evolution of species, a kind of special sequences, termed ultraconserved sequences (UCSs), have been inherited without any change, which strongly suggests those sequences should be crucial for the species to survive or adapt to the environment. However, the UCSs are still...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
The contribution of a directional preference of stiffness to the efficacy of prophylactic sacral dressings in protecting healthy and diabetic tissues from pressure injury: computational modelling studies
 
Abstract The sacral region is the most common site for pressure injuries (PIs) associated with lying in bed, and such sacral PIs often commence as deep tissue injuries (DTIs) that later present as open wounds. In complex patients, diabetes is common. Because, among other factors, diabetes affects connective...
OtoRhinoLaryngology
GSE85755 Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations
 
Contributors : Susanne C van den Brink ; Fanny Sage ; Ábel Vértesy ; Bastiaan Spanjaard ; Josi Peterson-Maduro ; Chloé S Baron ; Catherine Robin ; Alexander van OudenaardenSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerio ; Mus musculusIn many gene expression...
OtoRhinoLaryngology
GSE104345 FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes [microarray]
 
Contributors : Ho-Keun Kwon ; Christophe Benoist ; Diane MathisSeries Type : Expression profiling by arrayOrganism : Mus musculusMicroarray profiles of M176, M354 and WT FoxP3 -transdued (in vitro) and -Treg from mice from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader...
OtoRhinoLaryngology
GSE103296 Genome wide screen to identify HDAC5 association in the cultured striatal neurons
 
Contributors : Taniguchi Makoto ; Cowan W ChristopherSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPurpose: using next generation sequencing, we identify the HDAC5 assocaited genomic region in the mouse cultured striatal neurons. from # All Medicine...
OtoRhinoLaryngology
GSE104344 FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes [nanostring]
 
Contributors : HoKeun Kwon ; Christophe Benoist ; Diane MathisSeries Type : OtherOrganism : Mus musculusNanostring profiles of CD4+ T cells transduced with EV, WT or FoxP3 mutants from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2wY86Tj
OtoRhinoLaryngology
GSE104336 RNA-Sequencing of Drosophila melanogaster Head Tissue on High Sugar and High Fat Diets
 
Contributors : Wayne O Hemphill ; Osvaldo G Rivera ; Matthew E TalbertSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterObesity has been shown to increase risk for cardiovascular disease and type-2 diabetes. In addition, it has been implicated in aggravation...
OtoRhinoLaryngology
GSE104304 Genome-wide analysis of mRNA expression in control and ChRO1 depleted C2C12 (Myoblasts and Myotubes)
 
Contributors : Jinyoung Park ; Eun-Jung ChoSeries Type : Expression profiling by arrayOrganism : Mus musculusThe novel lncRNA ChRO1 (Chromatin ReOrganization associated lncRNA 1) which we discovered seems to be involved in myogenesis by association with heterochromatin reorganization during muscle...
OtoRhinoLaryngology
GSE97158 Transcriptional responses induced by controlled human malaria infection (CHMI)
 
Contributor : Julian RothenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWhole blood RNA-Seq was applied to investigate gene expression kinetics in Tanzanian males who underwent controlled malaria infection by intradermal injection with aseptic, purified, cryopreserved...
OtoRhinoLaryngology
GSE104335 Whole transcriptome (gene expression and splice isoform changes) profiling using Affymetrix Human Transcriptome Array 2.0
 
Contributors : John Blenis ; Gina LeeSeries Type : Expression profiling by arrayOrganism : Homo sapiensTranscriptome analysis of total RNA samples from human cell line (LAM 621-101, female)Global gene and splice isoform expression profiling was performed to get a comprehensive view of transcriptome...
OtoRhinoLaryngology
GSE104346 FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes
 
Series Type : Expression profiling by array ; OtherOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below. from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2fs7p9r
OtoRhinoLaryngology
GSE104331 Precise modulation of genome functions and live tracking of genome regions in CRISPR/dCas9 knock-in mice
 
Contributor : Yu ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculuswe demonstrated ex vivo and in vivo validation of dCas9 KI functions such as transcription from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2wW2tox
OtoRhinoLaryngology
GSE104193 Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signalling and malignant features in vitro and in vivo 
 
Contributors : Santiago Ramón y Cajal ; Marta SeséSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe performed a polysomal RNA-Seq screen in non-malignant breast epithelial (MCF10A) and TNBC (MDA-MB-231) cells exposed to normoxic or hypoxic conditions and/or treated...
OtoRhinoLaryngology
GSE104317 Treatment with Albumin (A)-Hydroxyoleic acid (HOA) complex restores sensorimotor function in rats with spinal cord injury: Efficacy and gene expression regulation
 
Contributors : Gerardo Avila-Martín ; Manuel Mata-Roig ; Iriana Galán-Arriero ; Julian S Taylor ; Xavier Busquets ; Pablo V EscribáSeries Type : Expression profiling by arrayOrganism : Rattus norvegicusSensorimotor dysfunction following incomplete spinal cord injury (SCI) is often characterized by...
OtoRhinoLaryngology
GSE99017 Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
 
Series Type : OtherOrganism : Homo sapiens ; Mus musculusN6-methyladenosine (m6A), installed by the Mettl3/Mettl14 methyltransferase complex, is the most prevalent internal mRNA modification. Whether m6A regulates mammalian brain development is unknown. Here we show that Mettl14 deletion in the embryonic...
OtoRhinoLaryngology
GSE104310 Gene Expression Profile of human hepatocellular carcinoma by RNA sequencing
 
Contributors : Yangyang Deng ; Yue ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe aim of the present study was to investigate biomarkers in the malignant process of HCC by high throughput sequencing. from # All Medicine by Alexandros G. Sfakianakis via...
OtoRhinoLaryngology
GSE87382 Dietary medium-chain saturated fatty acids induce gene expression of energy metabolism-related pathways in adipose tissue of abdominally obese subjects
 
Contributors : Juri C Matualatupauw ; Mette Bohl ; Søren Gregersen ; Kjeld Hermansen ; Lydia A AfmanSeries Type : Expression profiling by arrayOrganism : Homo sapiensHigh MC-SFA intake resulted in a downregulation of gene expression of pathways related to complement system and inflammation, and an...
OtoRhinoLaryngology
GSE104305 Differential gene expression induced by anti-cancer agent plumbagin is mediated by androgen receptor in prostate cancer cells
 
Contributors : Gaelle Rondeau ; Parisa Abedinpour ; Adrian Chrastina ; Jennifer Pelayo ; Per Borgstrom ; John WelshSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPlumbagin treatment of mice harboring PTEN-P2 tumors in the prostate or on prostate tissue maintained...
OtoRhinoLaryngology
GSE73520 Calcium treatment can delay tomato (Solanum lycopersicum L.) fruit senescence
 
Contributors : Tianbao Yang ; Lingfei ShangguanSeries Type : Expression profiling by high throughput sequencingOrganism : Solanum lycopersicumIn the present study, we demonstrated that application of CaCl2 to ‘Micro Tom’ tomato fruit (mature green stage) delayed fruit senescence and mature. from #...
OtoRhinoLaryngology
Autism-relevant traits interact with temporoparietal junction stimulation effects on social cognition: a high-definition transcranial direct current stimulation and electroencephalography study
 
Abstract The temporoparietal junction (TPJ) is implicated in mental and emotional state attribution, processes associated with autism-relevant traits. Transcranial direct current stimulation (tDCS) to the TPJ can influence social-cognitive performance. However, associations with electrophysiology and...
OtoRhinoLaryngology
Proteomics identifies GOLPH3 with a link between Golgi structure, cancer, DNA damage and protection from cell death [Minireview]
 
GOLPH3 is the first example of a Golgi resident oncogene protein. It was independently identified in multiple screens; first in proteomic-based screens as a resident protein of the Golgi apparatus, and second as an oncogene product in a screen for genes amplified in cancer. A third screen uncovered the...
THERAPY MEDICINE BY SFAKIANAKIS G.ALEXANDROS
Teva Announces Reintroduction of Generic Depo-Provera in the United States
 
JERUSALEM–(BUSINESS WIRE)–Sep. 25, 2017– Teva Pharmaceutical Industries Ltd., (NYSE: TEVA) today announced the reintroduction of the generic equivalent to Depo-Provera1 Contraceptive Injection (medroxyprogesterone acetate injectable suspension,… from Therapeutics via xlomafota13 on Inoreader http://ift.tt/2fAFwzO...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Efficacy and Persistence of Allogeneic Adipose-Derived Mesenchymal Stem Cells Combined with Hyaluronic Acid in Osteoarthritis After Intra-articular Injection in a Sheep Model
 
Tissue Engineering Part A , Vol. 0, No. 0. from Biomedical Engineering via xlomafota13 on Inoreader...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Synergistic Therapeutic Effect of Three-Dimensional Stem Cell Clusters and Angiopoietin-1 on Promoting Vascular Regeneration in Ischemic Region
 
Tissue Engineering Part A , Vol. 0, No. 0. from Biomedical Engineering via xlomafota13 on Inoreader...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Electrochemical investigation of the Eu3+/2+ redox couple in complexes with variable numbers of glycinamide and acetate pendant arms
 
Abstract: The Eu3+/2+ redox couple provides a convenient design platform for responsive pO2 sensors...
THERAPY MEDICINE BY SFAKIANAKIS G.ALEXANDROS
p,p′-Methoxyl-diphenyl diselenide-loaded polymeric nanocapsules as a novel approach to inflammatory pain treatment: Behavioral, biochemistry and molecular evidence
 
Publication date: 1 January 2018Source:European Journal of Pharmaceutical Sciences, Volume 111 Author(s): Marcel Henrique Marcondes Sari, Vanessa Angonesi Zborowski, Luana Mota Ferreira, Natália Silva Jardim, Allanna Valentini Barbieri, Letícia Cruz, Cristina Wayne NogueiraThe current...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Direct Sampling and Analysis of Atmospheric Particulate Organic Matter by Proton-Transfer-Reaction Mass Spectrometry
 
Analytical ChemistryDOI: 10.1021/acs.analchem.7b02582 from BioChemistry via xlomafota13 on...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Comparison between the Hypolipidemic Activity of Parsley and Carob in Hypercholesterolemic Male Rats
 
Hypercholesterolemia is commonly associated with obesity that leads to heart diseases and diabetes....
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Iterative Schemes to Solve Low-Dimensional Calibration Equations in Parallel MR Image Reconstruction with GRAPPA
 
GRAPPA (Generalized Autocalibrating Partially Parallel Acquisition) is a widely used parallel MRI...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
NbS2 Nanosheets with M/Se (M = Fe, Co, Ni) Codopants for Li+ and Na+ Storage
 
ACS NanoDOI: 10.1021/acsnano.7b06133 from Biomedical Engineering via xlomafota13 on Inoreader...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Recurrent synovial chondromatosis of the temporomandibular joint: report of two cases
 
Synovial chondromatosis is the most common tumour-like lesion that is found in the temporomandibular joint (TMJ). Although it is benign and self-limiting, it can recur. We retrospectively reviewed 274 cases that were treated in our department from 2001-16 and found two recurrences, the radiological,...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Removal of a sequestrum by a patient with medication-related osteonecrosis of the jaw
 
Medication-related osteonecrosis of the jaw (MRONJ) is a rare complication of dentoalveolar surgery after treatment with antiresorptive or antiangiogenic agents.1 Patients are diagnosed with MRONJ if they have or have had: current or previous treatment with antiresorptive or antiangiogenic agents, exposed...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Comparison of Emla cream and lidocaine injection for local anaesthetic before radiofrequency reduction of the inferior turbinates
 
We compared the effectiveness of local anaesthetic with Emla cream with that of an injection of lidocaine for radiofrequency reduction of the inferior turbinates. We studied 98 consecutive patients with hypertrophied inferior turbinates, 46 of whom were given Emla cream and 52 lidocaine injection. The...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Multidisciplinary team approach in the oral rehabilitation of patients with cleidocranial dysplasia to achieve a functional aesthetic outcome
 
Cleidocranial dysplasia is a hereditary congenital disorder that results in delayed ossification of midline structures, and is caused by mutations in the RunX2 (runt-related transcription factor 2) gene located on the short arm of chromosome 6. Successful treatment depends on multidisciplinary assessment...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Beneficial effect of botulinum toxin A on secondary ischaemic injury of skin flaps in rats
 
Botulinum toxin A (BTX-A) protects against primary ischaemia of skin flaps, but its effect on secondary ischaemia is unknown. We induced secondary arterial or venous ischaemia in skin flaps of 32 Wistar rats, and tested the effectiveness of BTX injected subcutaneously 12hours before the flap was raised....
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
P 25 Reference values for the cross-sectional area of the vagus nerve in healthy subjects – a high-resolution ultrasound study
 
Examination of peripheral nerves with high-resolution ultrasound (HRUS) now routinely complements electrophysiological studies in various diseases. Prerequisite for nerve HRUS are well-defined reference values. Notably, reference values of the vagus nerve (VN) are varying (Cartwright, 2008; López-Hernández,...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
P 24 Electrophysiological connectivity during oscillatory cycles of alpha activity and the BOLD-signal correlate in major depression
 
Major depressive disorder (MDD) belongs to the leading causes of disability worldwide. From an electrophysiological point of view, EEG-alpha activity and alpha phase synchronization seem to be possible biomarkers with diagnostic and prognostic value. In parallel, functional magnetic resonance imaging...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
P 23 fMRI-mapping of somatosensory finger representation in complex regional pain syndrome
 
Somatosensory deficits are often reported in patients with complex regional pain syndrome (CRPS). In particular reduced spatial tactile resolution is a typical clinical finding in CRPS patients. The detailed underlying mechanism for development and preservation of these deficits is not yet fully understood.However,...
OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE
Cancer in Peru: The Lancet Oncology
 
Ben Anderson talks about cancer care and cancer trends in Peru. from Cancer via xlomafota13 on Inoreader http://ift.tt/2fqUSDk

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