Reimplantation of an Extruding Cochlear Implant

xlomafota13 shared this article with you from Inoreader Reimplantation of an Extruding Cochlear Implant Via ear nose throat Ear Nose Throat J. 2021 Aug 23:1455613211039042. doi: 10.1177/01455613211039042. Online ahead of print. ABSTRACT Cochlear implants have successfully improved hearing in severe and profoundly deaf patients in addition to improving their quality of life. Implant extrusion and wound infection of a cochlear implant are one of the most common postoperative complications, although it does not occur frequently (1.5%-5% of cases).1,2 We present a case of an extruding coch lear implant with dehiscence that was successfully reimplanted, a procedure of which there have been few previous reports in the literature. PMID:34420408 | DOI:10.1177/01455613211039042 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Long-term audiological benefit with an active transcutaneous bone-conduction device: a retrospective cohort analysis

xlomafota13 shared this article with you from Inoreader Long-term audiological benefit with an active transcutaneous bone-conduction device: a retrospective cohort analysis Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Aug 23. doi: 10.1007/s00405-021-07031-w. Online ahead of print. ABSTRACT PURPOSE: To evaluate long-term audiological, surgical and safety outcomes of a complex patient cohort treated with an active transcutaneous bone-conduction device (tBCD). METHODS: This retrospective, monocentric cohort analysis involves 31 adults with conductive (CHL) and mixed hearing loss (MHL). For outcome analysis, study results were divided into short-term follow-up data (< 12 months) and long-term follow-up data (> 12 months). RESULTS: 31 patients with a total person-time of 90.4 years and an average number of 3.2 ± 1.5 preoperatively performed surgeries on the implanted side were investigated. Mean BCD-aided PTA4 thresholds were significantly lower than unaided PTA4AC before surgery (64.7 ± 16.1 dB HL; CHL 50.6 ± 10.6 dB HL; MHL 72.8 ± 12.8 dB HL) and did not change between short-te rm (42.3 ± 13.1 dB HL; CHL 35.8 ± 6.8 dB HL; MHL 45.2 ± 14.3 dB HL) and long-term (43.4 ± 10.0 dB HL; CHL 35.8 ± 4.3 dB HL; MHL 48.1 ± 9.6 dB HL) follow-up periods. Speech intelligibility in the Freiburg monosyllables test at 65 dB improved significantly, from 16.3 ± 21.5% (CHL 26.8 ± 19.0%; MHL 8.7 ± 20.5%) in the unaided condition to 82.7 ± 15.5% (CHL 90.0 ± 12.2%; MHL 79.4 ± 16.3%) in the short-term and 85.5 ± 13.2% (CHL 93.8 ± 7.9%; MHL 79.5 ± 13.3%) BCD-aided in the long-term follow-up periods. Ten minor procedure-related and 6 implant-related (5 minor, 1 major) AEs occurred over the total follow-up period. CONCLUSION: The device provides satisfactory audiological and speech benefit over long-term follow-up periods, up to 7 years. Explant rates were very low, while the overall rate of manageable AEs was high in this complex patient cohort. The device is considered a safe and effective option in the long-term hearing rehabilitation of patients with CHL and M HL. PMID:34424382 | DOI:10.1007/s00405-021-07031-w View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Dehiscence or thinning of bone overlying the superior semicircular canal in idiopathic intracranial hypertension

xlomafota13 shared this article with you from Inoreader Dehiscence or thinning of bone overlying the superior semicircular canal in idiopathic intracranial hypertension Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Aug 23. doi: 10.1007/s00405-021-07020-z. Online ahead of print. ABSTRACT STUDY DESIGN: Retrospective cohort. OBJECTIVES: The objective of the study is to evaluate a relationship between idiopathic intracranial hypertension (IIH) and superior semicircular canal dehiscence (SSCD) of bone overlying the superior semicircular canal (SSC). MATERIALS AND METHODS: A total of 57 (114 ears) individuals, 20 of whom were controls and 37 of whom were IIH, were included in the study. Individuals were evaluated with 0.8 mm slice thickness computed tomography (CT) images for SSC bony roof thickness and SSCD. Thickness of the bony roof over the SSC was graded from Grade 1 to Grade 4. Grade 3 was defined as pre-dehiscence and Grade 4 as dehiscence. RESULTS: Bony roof thickness was 1.25 mm in the control group and 0.76 mm in the IIH group. When bony roof thickness was compared between the groups, it was f ound to be significantly thinner in the IIH group (p = 0.012). In the IIH group, while dehiscence was detected in 25 of 74 ears, no dehiscence was detected in 49 ears. In the control group, while dehiscence was detected in 5 ears, no dehiscence was detected in 35 ears. The difference is statistically significant (p = 0.015). The correlation between bony roof thickness and cerebrospinal fluid (CSF) pressure in the IIH group was not statistically significant (p = 0.343; rho = 0.110). The correlation between bony roof thickness and age in the IIH group was not statistically significant (p = 0.082; rho = - 0.164). CONCLUSION: Increased CSF pressure in patients with IIH may cause chronic, progressive, and irreversible damage to the bone of the SSC and, according to our study, the rate of SSCD was found to be high in IIH patients. PMID:34424380 | DOI:10.1007/s00405-021-07020-z View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Interactive live-stream surgery contributes to surgical education in the context of contact restrictions

xlomafota13 shared this article with you from Inoreader Interactive live-stream surgery contributes to surgical education in the context of contact restrictions Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Aug 23. doi: 10.1007/s00405-021-06994-0. Online ahead of print. ABSTRACT BACKGROUND: Attendance teaching is the predominant teaching method at universities but needs to be questioned in the context of digital transformation. This study establishes and evaluates a method to accomplish electronic learning to supplement traditional attendance courses. MATERIALS AND METHODS: Surgery was transmitted in real-time conditions via an online live stream from the surgical theater. Visualization was transferred from a fully digital surgical microscope, an endoscope or an environmental camera in high definition quality. Students were able to participate at home from their personal computer. After following the surgery, they participated in an online-evaluation. RESULTS: A total of 65 students participated in the live stream. The majority of students (61.54%) indicated a significant subjective increase in knowledge after participation. The majority of students (53.85%) indicated that live surgeries should be offered as a permanent component in addition to classroom teaching. Likewise, a broader offer was desired by many students (63.08%). CONCLUSIONS: Live streaming of surgery is a promising approach as an alternative or supplement to traditional attendance teaching. An expansion of digital teaching can be explicitly supported on the basis of this study. PMID:34424381 | DOI:10.1007/s00405-021-06994-0 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cervical Subarachnoid Drain for the Treatment of Cerebrospinal Fluid Leak: 2-Dimensional Operative Video

xlomafota13 shared this article with you from Inoreader Cervical Subarachnoid Drain for the Treatment of Cerebrospinal Fluid Leak: 2-Dimensional Operative Video Via leak of cerebrospinal fluid Oper Neurosurg (Hagerstown). 2021 Aug 23:opab292. doi: 10.1093/ons/opab292. Online ahead of print. ABSTRACT Cerebrospinal fluid (CSF) leak is a common phenomenon encountered by the neurosurgeon. It is most commonly come across after a neurosurgical procedure, but it can be seen idiopathically. Treatment usually ranges from conservative management through cerebrospinal fluid diversion to direct surgical repair. Continuous CSF drainage provides a path for diversion and allowing the site of the dural injury to heal effectively.1 Cervical subarachnoid drain is a safe and effective alternative when lumbar access is contraindicated or not achievable.2 Here we present a case of a 22-yr-old female with progressive symptomatic positional headaches due to a CSF leak from a prior deformity surgery treated with a cervical subarachnoid drain after a failed attempt at a direct repair. This 2-dimensional video illustrates the technique used for the placemen t of a cervical subarachnoid drain for the treatment of symptomatic CSF leak. Patient consented to the procedure and for the publication of their image. PMID:34424330 | DOI:10.1093/ons/opab292 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Improving speech characteristics of young adults with congenital dysarthria: An exploratory study comparing articulation training and the Beatalk method

xlomafota13 shared this article with you from Inoreader Improving speech characteristics of young adults with congenital dysarthria: An exploratory study comparing articulation training and the Beatalk method Via Journal of Communication Disorders (open access) Publication date: Available online 20 August 2021 Source: Journal of Communication Disorders Author(s): Michal Icht View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Contralateral hearing loss in children with a unilateral enlarged vestibular aqueduct

xlomafota13 shared this article with you from Inoreader Contralateral hearing loss in children with a unilateral enlarged vestibular aqueduct Via International Journal of Pediatric Otorhinolaryngology Publication date: November 2021 Source: International Journal of Pediatric Otorhinolaryngology, Volume 150 Author(s): E.A. van Beeck Calkoen, R.J.E. Pennings, J. Smits, S. Pegge, L.J.C. Rotteveel, P. Merkus, B.M. Verbist, E. Sanchez, E.F. Hensen View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Hsa_circ_0023990 promotes tumor growth and glycolysis in dedifferentiated TC via targeting miR-485-5p/FOXM1 axis

xlomafota13 shared this article with you from Inoreader Hsa_circ_0023990 promotes tumor growth and glycolysis in dedifferentiated TC via targeting miR-485-5p/FOXM1 axis Via radioactive iodine Endocrinology. 2021 Aug 20:bqab172. doi: 10.1210/endocr/bqab172. Online ahead of print. ABSTRACT BACKGROUND: During the transformation to dedifferentiated TC types, the ability of papillary thyroid carcinomas (PTC) to concentrate radioactive iodine might be lost, raising difficulty for the current therapy. Circular RNAs (circRNAs) were proved to be implicated in the progression of various cancers. In this study, we aimed to investigate the functional role and mechanism of hsa_circ_0 023990 in dedifferentiated TC. METHODS: The expression pattern of genes were detected utilizing qPCR or western blot assays. Cell proliferation was determined by CCK8, colony formation, EdU and cell cycle assays. Glycolysis was assessed using glucose uptake and lactate production assays. Luciferase reporter assay was performed to examine the interactions between miR-485-5p and hsa_circ_0023990 or FOXM1. Xenograft assay was allowed for observation of tumor growth in vivo. RESULTS: Hsa_circ_0023990 and FOXM1 were upregulated in dedifferentiated TC tissues and cell lines. The higher level of hsa_circ_0023900 could stimulate the proliferation and glycolysis of dedifferentiated TC cells via positively regulating FOXM1. Mechanistically, miR-485-5p was demonstrated to interact with hsa_circ_0023990 and FOXM1 and involved in the regulation of has_circ_0023990 and FOXM1 in TC biological processes. CONCLUSION: Our results discovered the functional network of hsa_circ_0023990 in dedifferentiated TC development by facilitating cell proliferation and glycolysis via miR-485-5p/FOXM1 axis, implying that hsa_circ_0023990 might be a potential therapeutic target for the dedifferentiated TC treatment. PMID:34414414 | DOI:10.1210/endocr/bqab172 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Contracture Treatment With 5-FU

xlomafota13 shared this article with you from Inoreader Contracture Treatment With 5-FU Via ear nose throat Ear Nose Throat J. 2021 Aug 20:1455613211039037. doi: 10.1177/01455613211039037. Online ahead of print. ABSTRACT We present a case of a 53-year-old female patient who was treated with 5-Fluorouracil (5-FU) after postsurgical contracture. A review of the literature regarding the use of 5-FU injections as a minimally invasive way to treat contracture was performed. We describe that the use of 5-FU injections is the preferred method for the effective treatment of contracture wi th minimal risk to the patient. PMID:34414812 | DOI:10.1177/01455613211039037 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Pott's Puffy Tumor

xlomafota13 shared this article with you from Inoreader Pott's Puffy Tumor Via ear nose throat Ear Nose Throat J. 2021 Aug 20:1455613211039031. doi: 10.1177/01455613211039031. Online ahead of print. ABSTRACT Pott's puffy tumor is a potential complication of acute frontal sinusitis, characterized by subperiosteal abscess and osteomyelitis of the frontal bone. It can be managed with a combination of open and endoscopic sinus surgery and intravenous antibiotic therapy. In the current report, a 15-year-old male presented with a classic case of Pott's puffy tumor which was managed with bilateral ethmoidectomies, frontal sinusotomies, and frontal sinus trephination, resulting in discharge on intravenous antibiotic therapy and subsequent complete resolution of symptoms. PMID:34414793 | DOI:10.1177/01455613211039031 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Frequency and Clinical Assessment of COVID-19 in Patients With Chronic Rhinosinusitis

xlomafota13 shared this article with you from Inoreader The Frequency and Clinical Assessment of COVID-19 in Patients With Chronic Rhinosinusitis Via ear nose throat Ear Nose Throat J. 2021 Aug 20:1455613211038070. doi: 10.1177/01455613211038070. Online ahead of print. ABSTRACT BACKGROUND: Chronic rhinosinusitis (CRS), as an inflammatory airway disease, could be a risk factor for COVID-19 patients. This study aimed to investigate the frequency and severity of symptoms of COVID-19 in patients with CRS and to assess the association between the status of CRS symptoms and the quality of life (QoL) of the patients. METHODS: In this obse rvational and cross-sectional study, 207 adult CRS patients participated. The patients, who presented the symptoms of COVID-19, were examined by taking the reverse transcription-polymerase chain reaction test. A questionnaire was completed by each patient, regarding their demographic and clinical data. In addition, the GA2LEN and Sino-Nasal Outcome Test (SNOT-22) standard questionnaires were used to identify the comorbid allergic condition and QoL of CRS patients. RESULTS: The frequency of patients with COVID-19 was 25 (12.1%) of which 22 were treated as outpatients, 2 of them admitted in wards and 1 at intensive care unit. The severity of hyposmia in the patients was 2 (8%) as mild, 5 (20%) moderate, and 11 (72%) as anosmia. The most common allergic and underlying comorbid diseases were allergic rhinitis (88%) and thyroid disorders (28%). Further, the average SNOT-22 score in 4 SNOT-22 domains (nasal, otologic, sleep, and emotional symptoms) was significantly decre ased in CRS patients after a period of one year since the pandemic started (40.1 ± 18.0 vs. 46.3 ± 17.7; P < .0001). DISCUSSION: This study showed a low frequency of COVID-19 in patients with CRS and about the same rate of infection positivity in the general population; therefore, we concluded that CRS could not be considered as a risk factor for COVID-19. Interestingly, the lower average score of SNOT-22 after one year of the pandemic in the patients with CRS confirmed the necessity for performing the standard health protocols by the patients. PMID:34414811 | DOI:10.1177/01455613211038070 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.