Dysphagia in a patient with ankylosing spondylitis: A case report

paythelady.612 shared this article with you from Inoreader Dysphagia in a patient with ankylosing spondylitis: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1639-1645. doi: 10.12998/wjcc.v9.i7.1639. ABSTRACT BACKGROUND: Ankylosing spondylitis (AS) is a systematic and rheumatic disease, which causes multiple symptoms. However, dysphagia due to the formation of a giant anterior cervical osteophyte is rare in patients with AS. CASE SUMMARY: We present the case of a 65-year-old male patient who was diagnosed with AS and visited the hospital with a complaint of progressive dysphagia. The appropriate imaging examinations indicated that a giant anterior cervical osteo-phyte at C3-4 caused esophageal compression, which led to dysphagia. An operation for resection was performed without complications. CONCLUSION: This case demonstrates that a large cervical osteophyte may be the cause of dysphagia in patients with AS, and early accurate diagnosis and surgical treat-ment are very important for the improvement of symptoms. Anterior cervical discectomy an d fusion are extremely effective and should be taken into consideration. PMID:33728307 | PMC:PMC7942043 | DOI:10.12998/wjcc.v9.i7.1639 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature

paythelady.612 shared this article with you from Inoreader Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1705-1713. doi: 10.12998/wjcc.v9.i7.1705. ABSTRACT BACKGROUND: The coronavirus disease 2019 (COVID-19) caused by novel coronavirus 2019 in December 2019 has spread all around the globe and has caused a pandemic. There is still no current effective guidance on the clinical management of COVID-19. Mesenchymal stem cell therapy has been shown to be one of the therapeutic approaches to alleviate pneumonia and symptoms through their immunomo-dulatory effect in COVID-19 patients. CASE SUMMARY: We describe the first confirmed case of COVID-19 in Hangzhou to explore the role of human menstrual blood-derived stem cells (MenSCs) in the treatment of COVID-19. Moreover, we review the immunomodulation effect including non-specific and specific immune functions of MenSCs for the therapy of COVID-19. CONCLUSION: MenSCs can be helpful to find a promising therapeutic approach for COVID-19. PMID:33728315 | PMC:PMC7942055 | DOI:10.12998/wjcc.v9.i7.1705 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Review of the risk factors for SARS-CoV-2 transmission

paythelady.612 shared this article with you from Inoreader Review of the risk factors for SARS-CoV-2 transmission Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1499-1512. doi: 10.12998/wjcc.v9.i7.1499. ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, which has lasted for nearly a year, has made people deeply aware of the strong transmissibility and pathogenicity of SARS-CoV-2 since its outbreak in December 2019. By December 2020, SARS-CoV-2 had infected over 65 million people globally, resulting in more than 1 million deaths. At present, the exact animal origin of SARS-CoV-2 remains unclear and antiviral vaccines are now undergoing clinical trials. Although the social order of human life is gradually returning to normal, new confirmed cases continue to appear worldwide, and the majority of cases are sporadic due to environmental factors and lax self-protective consciousness. This article provides the latest understanding of the epidemiology and risk factors of nosocomial and community transmission of SARS-CoV-2, as well as strategies to diminish the risk of transmission. We believe that our review will help the public correctly understand and cope with SARS-CoV-2. PMID:33728294 | PMC:PMC7942044 | DOI:10.12998/wjcc.v9.i7.1499 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Pure transvaginal natural orifice transluminal endoscopic surgery right hemicolectomy for colon cancer: A case report

paythelady.612 shared this article with you from Inoreader Pure transvaginal natural orifice transluminal endoscopic surgery right hemicolectomy for colon cancer: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1714-1719. doi: 10.12998/wjcc.v9.i7.1714. ABSTRACT BACKGROUND: Pure natural orifice transluminal endoscopic surgery (NOTES) for colorectal cancer is a complex procedure and rarely used in clinical practice because of the ethical concerns and technical challenges, including loss of triangulation, in-line orientation, and instrument collision. Transvaginal (v) NOTES, however, can overcome these technical challenges. We report a case of pure vNOTES right hemicolectomy for colon cancer, attached with surgical video. CASE SUMMARY: A 65-year-old woman with a 2-year history of intermittent diarrhea was diagnosed with ascending colon adenocarcinoma by colonoscopy and biopsy. Pure vNOTES right hemicolectomy was performed with complete mesocolic excision by well-experienced surgeons. The operative time was 200 min and the estimated blood loss was 30 mL. No intraoperative or postoperative complications oc curred within 30 d after the surgery. The visual analog scale pain score on postoperative day 1 was 1 and dropped to 0 on postoperative days 2 and 3. The patient was discharged at postoperative day 6. The pathologic specimen had sufficient clear resection margins and 14 negative harvested lymph nodes. CONCLUSION: vNOTES right hemicolectomy, performed by well-experienced surgeons, overcomes the technical challenges of pure NOTES and may be feasible for colon cancer. PMID:33728316 | PMC:PMC7942039 | DOI:10.12998/wjcc.v9.i7.1714 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Use of three dimensional-printing in the management of floating aortic thrombus due to occult aortic dissection: A case report

paythelady.612 shared this article with you from Inoreader Use of three dimensional-printing in the management of floating aortic thrombus due to occult aortic dissection: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1755-1760. doi: 10.12998/wjcc.v9.i7.1755. ABSTRACT BACKGROUND: Floating thrombus within the thoracic aorta is a rare entity but may cause systemic embolism. The pathogenesis of floating aortic thrombi is not yet fully understood. No definitive guidelines are available for the management of floating aortic thrombus. CASE SUMMARY: We report a 48-year-old patient, without a history of trauma and infection, who presented with sudden severe back pain. A floating thrombus within the aortic arch was found by computed tomography angiography (CTA). No evidence of coagulopathies was found. However, with the assistance of a three dimensional-printed model, this floating thrombus was identified to be caused by occult aortic dissection (AD). Subsequently, an emergency thoracic endovascular repair was performed. The patient's back pain was rapidly alleviated postoperatively. CTA at 1 year showed no filling d efect in the stent-graft and aorta. CONCLUSION: Occult AD is a potential factor causing floating aortic thrombi, endovascular stent-graft exclusion may be an optimal therapeutic choice with promising results. Moreover, the combination of CTA and three dimensional-printed models can contribute to the diagnosis and treatment of floating aortic thrombi due to occult AD. PMID:33728322 | PMC:PMC7942031 | DOI:10.12998/wjcc.v9.i7.1755 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Hyperglycemic hemianopia: A case report

paythelady.612 shared this article with you from Inoreader Hyperglycemic hemianopia: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1720-1727. doi: 10.12998/wjcc.v9.i7.1720. ABSTRACT BACKGROUND: Nonketotic hyperglycemia (NKH) is characterized by hyperglycemia with little or no ketoacidosis. Diverse neurological symptoms have been described in NKH patients, including choreoathetosis, hemiballismus, seizures, and coma in severe cases. Homonymous hemianopia, with or without occipital seizures, caused by hyperglycemia is less readily recognized. CASE SUMMARY: We describe a 54-year-old man with NKH, who reported seeing round, colored flickering lights with right homonymous hemianopia. Cranial magnetic resonance imaging demonstrated abnormalities in the left occipital lobe, with decreased T2 signal of the white matter, restricted diffusion, and corresponding low signal intensity in the apparent diffusion coefficient map. He responded to rehydration and a low-dose insulin regimen, with improvements of his visual field defect. < p>CONCLUSION: Patients with NKH may present focal neurologic signs. Hyperglycemia should be taken into consideration when making an etiologic diagnosis of homonymous hemianopia. PMID:33728317 | PMC:PMC7942036 | DOI:10.12998/wjcc.v9.i7.1720 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Intra-arterial thrombolysis for early hepatic artery thrombosis after liver transplantation

paythelady.612 shared this article with you from Inoreader Intra-arterial thrombolysis for early hepatic artery thrombosis after liver transplantation Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1592-1599. doi: 10.12998/wjcc.v9.i7.1592. ABSTRACT BACKGROUND: Early hepatic artery thrombosis (E-HAT) is a serious complication after liver transplantation (LT), which often results in graft failure and can lead to patient deaths. Treatments such as re-transplantation and re-anastomosis are conventional therapeutic methods which are restricted by the shortage of donors and the patient's postoperative intolerance to re-laparotomy. Due to the advances in interventional techniques and thrombolytics, endovascular treatments are increasingly being selected by more and more centers. This study reviews and reports our single-center experience with intra-arterial thrombolysis as the first choice therapy for E-HAT after deceased donor LT. AIM: To evaluate the feasibility and reasonability of intra-arterial thrombolysis for E-HAT after deceased donor LT. METHODS: A total of 147 patients who underw ent deceased donor LT were retrospectively reviewed in our hospital between September 2011 and December 2016. Four patients were diagnosed with E-HAT. All of these patients underwent intra-arterial thrombolysis with alteplase as the first choice therapy after LT. The method of arterial anastomosis and details of the diagnosis and treatment of E-HAT were collated. The long-term prognosis of E-HAT patients was also recorded. The median follow-up period was 26 mo (range: 23 to 30 mo). RESULTS: The incidence of E-HAT was 2.7% (4/147). E-HAT was considered when Doppler ultrasonography showed no blood flow signals and a definite diagnosis was confirmed by immediate hepatic arterial angiography when complete occlusion of the hepatic artery was observed. The patients were given temporary thrombolytics (mainly alteplase) via a 5-Fr catheter which was placed in the proximal part of the thrombosed hepatic artery followed by continuous alteplase using an infusion pump. Alteplase do se was adjusted according to activated clotting time. The recanalization rate of intra-arterial thrombolysis in our study was 100% (4/4) and no thrombolysis-related mortality was observed. During the follow-up period, patient survival rate was 75% (3/4), and biliary complications were present in 50% of patients (2/4). CONCLUSION: Intra-arterial thrombolysis can be considered first-line treatment for E-HAT after deceased donor LT. Early diagnosis of E-HAT is important and follow-up is necessary even if recanalization is successful. PMID:33728302 | PMC:PMC7942050 | DOI:10.12998/wjcc.v9.i7.1592 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Mucinous appendiceal neoplasm: A case report

paythelady.612 shared this article with you from Inoreader Mucinous appendiceal neoplasm: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1728-1733. doi: 10.12998/wjcc.v9.i7.1728. ABSTRACT BACKGROUND: Primary appendiceal tumors are histologically diverse and have an insidious onset and few specific clinical manifestations. In the majority of cases, these tumors are discovered after appendectomy during pathological exam of the resected tissue. Treatment may include appendectomy (simple or radical) and right hemicolectomy depending on factors such as histological type, tumor size and lymph node/organ involvement. The aim of this case study is to describe a rare case of a giant appendicular mucocele and raise awareness of this condition and its management options and follow-up protocol. CASE SUMMARY: We present the case of a 43-year-old patient who presented to our emergency department with mild right lower quadrant pain. After the initial check-up and imaging exams, he underwent surgery, where a giant 20 cm × 13 cm appendicular tu mor was found and resected. Appendicular mucocele was suspected due to the macroscopic appearance and was later confirmed by the pathological exam. The patient's postoperative evolution was uneventful, and after discharge, he was included in our follow-up program. CONCLUSION: In conclusion, mucinous appendiceal neoplasms embody a rare pathology; they are asymptomatic or have few, unspecific clinical signs and in many cases are discovered after appendectomy. PMID:33728318 | PMC:PMC7942034 | DOI:10.12998/wjcc.v9.i7.1728 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Balloon-assisted endoscopic submucosal dissection for treating small intestinal lipomas: Report of two cases

paythelady.612 shared this article with you from Inoreader Balloon-assisted endoscopic submucosal dissection for treating small intestinal lipomas: Report of two cases Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1631-1638. doi: 10.12998/wjcc.v9.i7.1631. ABSTRACT BACKGROUND: Most small intestinal lipomas are treated surgically, and some require repeated surgeries for multiple lipomas. However, application of endoscopic submucosal dissection (ESD) technology in the deep small intestine is rarely reported owing to the special anatomical structure of the small intestine, medical equipment limitations, and the lack of relevant experience among endoscopists. CASE SUMMARY: Two patients with small intestinal lipomas treated at the Air Force Medical Center from November 2015 to September 2019 were selected to undergo balloon-assisted ESD to treat the lipomas and explore the technical feasibility and safety of ESD for treating small intestinal lipomas. The two patients successfully underwent balloon-assisted ESD to treat four small intestinal lipomas, with a complete resection rate of 100% (4/4), without intraop erative or postoperative bleeding, perforation, or other complications. After 3-6 mo of postoperative follow-up, the clinical symptoms caused by the lipomas were significantly relieved or disappeared after treatment. CONCLUSION: Balloon-assisted ESD is a safe and reliable new method for treating deep intestinal lipomas and shows good clinical feasibility. PMID:33728306 | PMC:PMC7942049 | DOI:10.12998/wjcc.v9.i7.1631 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Reconstructing abdominal wall defects with a free composite tissue flap: A case report

paythelady.612 shared this article with you from Inoreader Reconstructing abdominal wall defects with a free composite tissue flap: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1734-1740. doi: 10.12998/wjcc.v9.i7.1734. ABSTRACT BACKGROUND: Reconstructive repair of huge full-thickness abdominal wall defects following debridement for abdominal electric burns remains a clinically challenging task. An ideal abdominal wall repair means a re-closure of the defected abdominal wall with pedicled neurovascular myofascial flaps, restoration of the abdominal wall integrity, and maintenance of the abdominal wall muscle tension to prevent the occurrence of abdominal wall hernia. When treating huge full-thickness defects, composite autologous tissue flaps are a good option for the repair. CASE SUMMARY: This study reported the case of a 43-year-old male patient suffering from full-thickness abdominal wall defects complicated with necrosis of multiple bowel segments and duodenal leak following high-voltage burns involving the left upper limb and abdomen. After debridement for abdomin al electric burns and end-to-end anastomosis for the necrotic bowels, reconstruction with acellular dermal matrix grafting and vacuum sealing drainage were performed for temporary abdominal closure. The remaining 18 cm × 15 cm full-thickness abdominal wall defect was repaired using a combined anterolateral thigh and tensor fascia lata free flap. The proposed method achieved the functional reconstruction of the abdominal wall. CONCLUSION: This approach restored the abdominal wall integrity, maintained certain muscle tension, avoided abdominal hernia, reached satisfactory aesthetic effect, and resulted in no complications in the grafting regions. PMID:33728319 | PMC:PMC7942038 | DOI:10.12998/wjcc.v9.i7.1734 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Efficacy and safety of short duration radiotherapy combined with chemotherapy for advanced rectal cancer

paythelady.612 shared this article with you from Inoreader Efficacy and safety of short duration radiotherapy combined with chemotherapy for advanced rectal cancer Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 6;9(7):1524-1531. doi: 10.12998/wjcc.v9.i7.1524. ABSTRACT BACKGROUND: Radiotherapy or chemoradiotherapy is widely used for the treatment of rectal cancer preoperatively. Although the combination of radiotherapy and chemotherapy as an established preoperative neoadjuvant therapy shows high efficacy in the treatment of rectal cancer, some patients experience a response of poor tolerance and outcomes due to the long duration radiotherapy. The study compared short duration radiotherapy plus chemotherapy vs long duration radiotherapy plus chemotherapy for rectal cancer to determine whether short duration radiation treatment should be considered to diminish complications, reduce risk of recurrence and improve survival in patients with rectal cancer. AIM: To evaluate the efficacy and safety of short duration radiotherapy combined with chemotherapy for the treatment of advanced rectal cancer. MET HODS: One hundred patients with stage IIIB or higher severe rectal cancer were selected as the study subjects at The First Affiliated Hospital of Hebei North University between December 2018 and December 2019. The patients were assigned to different groups based on the treatment regimens. Fifty patients who received preoperative short durations of radiotherapy plus chemotherapy were enrolled in an observation group and fifty patients who received conventional radiotherapy and chemotherapy were enrolled in a control group. Colonoscopic biopsy was performed for all patients with pathological diagnosis of rectal cancer. The expression of tumor-related factors such as RUNX3 and Ki-67 was quantitatively analyzed using immunohistochemistry in the tissues of the patients before and after treatment. Moreover, the duration of procedure, the amount of bleeding during the operation, the anus-conserving rate, the incidence of postoperative complications (wound infection, anastomotic leakage, po stoperative intestinal obstruction, etc.) and postoperative pathology were compared between the two groups. The overall survival rate, recurrence rate and distant metastasis rate were also compared through postoperative reexamination and regular follow-up. RESULTS: There was no significant difference in the positive expression rate of RUNX3 and Ki-67 between the two groups before the treatment (P > 0.05). Compared with the pretreatment value, the positive rate of RUNX3 was increased and the positive rate of Ki-67 was decreased in both groups after the treatment (all P < 0.05). The incidence of leukopenia, thrombocytopenia, neutropenia and diarrhea were higher in the observation group than in the control group (all P < 0.05). There was no significant difference in the incidence of anemia, fatigue, neurotoxicity and nausea and vomiting between the two groups (all P > 0.05). No significant difference was observed in the duration of p rocedure, intraoperative bleeding, the anus-conserving rate and the incidence of postoperative complications between the two groups (P > 0.05). After 1 year of follow-up, the 1-yr survival rate was 80.0% in the observation group and 68.0% in the control group, the recurrence rate was 8.0% in the observation group and 10.0% in the control group, the distant metastasis rate was 6.0% in the observation group and 8.0% in the control group difference (all P < 0.05). CONCLUSION: Short duration radiotherapy combined with chemotherapy can improve the cure rate, prolong the survival time and reduce the incidence of complications in patients with advanced rectal cancer. PMID:33728296 | PMC:PMC7942029 | DOI:10.12998/wjcc.v9.i7.1524 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.