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Τετάρτη 3 Μαρτίου 2021

Otological Assessment in Head Injury Patients: A Prospective Study and Review of Literature

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Abstract

Head injuries constitute a tragic problem invariably in under-developed, developed and developing countries. The concomitant otological injuries often go unnoticed. The purpose of this study was to assess the various otological manifestations following head injuries. Prospective study with review of literature using PubMed database was done. All the patients were evaluated for their presenting symptoms and signs. Audiological investigations including PTA (Pure tone audiometry), OAE (Otoacoustic emission), Impedance-Audiometry and BERA were done. HRCT temporal bone was advised in cases of suspicion. Relevant literature was reviewed to calculate the pooled prevalence rates. Random-effects model to synthesize overall effects was used. Heterogeneity was evaluated with the I2 statistic. Of 53 patients enrolled in the study, RTA was the most common mode of injury. The audiometric findings showed SNHL, CHL and mixed HL in 34, 20 and 18% of patients respective ly. HRCT showed Longitudinal fracture (n = 17; 53.12%); isolated mastoid bone fracture (n = 9; 28.12%), transverse (n = 3; 9.37%) and isolated EAC fracture in (n = 3; 9.37%) patients. The pooled prevalence (n = 1106 patients) of SNHL, CHL, Mixed HL and Normal hearing were—35% (95%CI, 18–55%; I2 = 95.20%; P < 0.00), 24% (95%CI, 16–33%; I2 = 80.01%; P < 0.00), 15%(95%CI, 9–23%; I2 = 79.64%; P < 0.00) and 30% (95%CI, 3–66%; I2 = 98.71%; P < 0.00) respectively. The pooled prevalence (n = 4191 patients) of longitudinal, Transverse, mixed and other fractures were—44% (95%CI, 3–66%;I2 = 99.48%; P < 0.00), 9% (95% CI, 4–16%; I2 = 95.95%; P < 0.00), 4% (95%CI, 1–8%; I2 = 94.13%; P < 0.00) and 1% (95%CI, 0–4%; I2 = 90.37% ; P < 0.00) respectively. In patients with head injury coordination between the trauma-surgeon, neurosurgeon and otologist is must to improve the long-term outcomes.

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Chronic obstructive Eustachian tube dysfunction: CT assessment with Valsalva maneuver and ETS-7 score

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journal.pone.0247708.g003&size=inline

by Diletta Angeletti, Annalisa Pace, Giannicola Iannella, Valeria Rossetti, Andrea Colizza, Irene Claudia Visconti, Giampiero Gulotta, Daniela Messineo, Marco de Vincentiis, Antonio Greco, Ferdinando D'Ambrosio, Giuseppe Magliulo

Chronic obstructive Eustachian tube dysfunction (ETD) is a common disorder of the middle ear. In recent years, two main diagnostic tools have become available: Eustachian tube score (ETS-7) and computed tomography (CT) combined with Valsalva maneuver. The aim of this study is to evaluate the outcomes of ETS-7 and CT in a group of patients affected by middle ear atelectasis with a strong suspicion of ETD. Three males and nine females, affected by middle ear atelectasis with retraction of the TM were enrolled. Each patient underwent to Eustachian tube dysfunction evaluation adopting the ETS-7 score and a temporal bone CT with Valsalva maneuver. The ears analyzed at steady state were divided into 2 groups: ETS
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Tinnitus and associations with chronic pain: The population-based Tromsø Study (2015–2016)

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journal.pone.0247880.g002&size=inline

by Jannike H-L Ausland, Bo Engdahl, Bente Oftedal, Ólöf A. Steingrímsdóttir, Christopher S. Nielsen, Laila A. Hopstock, Magnar Johnsen, Oddgeir Friborg, Jan H. Rosenvinge, Anne E. Eggen, Norun H. Krog

Tinnitus and pain have many similarities. Both are subjective sensations that may turn chronic, they are often accompanied by hypersensitivity in their respective sensory system, and overlapping brain changes have been observed. Since no population study has examined the empirical association between chronic pain and tinnitus, the present study aimed to explore the relationship in a general adult population. We used data from the seventh survey of the Tromsø Study (2015–2016). Participants (aged ≥40) responded to questions about pain and tinnitus. Using multiple logistic regression, we analysed the adjusted relationship between chronic pain and tinnitus in the full sample (n = 19,039), using several tinnitus definitions ranging from tinnitus >5 minutes within the past 12 months (broadest definition) to at least weekly and highly bothersome tinnitus (strictest definition). We also analysed relationships between number of body regions with pain, pain intensity and bothering, an d tinnitus >5 minutes, among participants with chronic pain (n = 11,589). We found an association between chronic pain and tinnitus that was present irrespective of tinnitus definition, but was stronger with more bothersome tinnitus. With chronic pain, the odds of tinnitus >5 minutes was 64% higher, while odds of at least weekly, highly bothersome tinnitus was 144% higher than without chronic pain. Among participants with chronic pain, the number of pain regions was the pain variable most strongly associated with tinnitus >5 minutes (OR = 1.17 (95% CI: 1.14–1.20) for an increase of one region), whereas the other pain variables (intensity and bothering) showed weaker associations. All chronic pain variables had significant interactions with age, with the strongest associations for the youngest individuals (40–54 years). Our findings support the existence of an association between chronic pain and tinnitus and emphasises the importance of examining for comorbid pain in ti nnitus patients to provide a more comprehensive treatment of tinnitus.
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Topical ciprofloxacin as treatment for rhinoscleroma in a series of 23 patients

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Abstract

There is no current consensus on treatment of rhinoscleroma, with no treatment shown to achieve reliable long‐term cure of the disease. Oral ciprofloxacin for three months is currently one of the most favored options for treatment of rhinoscleroma. In a series of 23 patients, Topical ciprofloxacin was investigated as a novel option for treatment of rhinoscleroma and was found to be effective in treating the disease in all patients after 12‐24 weeks. However, 5 cases of recurrence were encountered between 12‐18 months after end of treatment. Topical treatment with ciprofloxacin in cases of rhinoscleroma limited to the nose may be preferable to systemic treatment, with similar efficacy and lower risk of side effects.

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Die hereditäre hämorrhagische Teleangiektasie mit unklaren Tumoren der Leber

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Laryngorhinootologie
DOI: 10.1055/a-1387-8050



Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

Article in Thieme eJournals:
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Postoperative Hypokalzämie – die häufigste Komplikation der endokrinen Chirurgie der Halsregion: Akutes Management

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Laryngorhinootologie
DOI: 10.1055/a-1381-8286

Hintergrund In Deutschland sind jährlich ca. 8000 Patienten nach Eingriffen an Schilddrüse, Nebenschilddrüse und Larynx von einem behandlungsbedürftigen postoperativen Hypoparathyreoidismus betroffen. Die Patienten leiden im Akutstadium der Hypokalzämie an Parästhesien und nicht selten auch über viele Jahre hinweg unter der Angst vor einem erneuten körperlichen Kontrollverlust bei schweren postoperativen Tetanien. Fragestellung/Ziel Ziel dieser Arbeit ist es, für die Wichtigkeit des Managements des postoperativen Hypoparathyreoidismus in der endokrinen Chirurgie der Halsregion zu sensibilisieren, einen praktikablen Diagnostikpfad aufzuzeigen und so die effektive Therapie zu ermöglichen. Material und Methode Narratives Review mit Auswertung und Diskussion von relevanten klinischen Originalarbeiten und Expertenempfehlungen. Ergebnisse und Diskussion Die frühzeitige postoperative Diagnosestellung nach Eingriffen im Halsbereich mittels Bestimmung von Kalzium und Parathormon ermöglicht den rechtzeitigen Therapiebeginn. Aktives Vitamin D sichert dabei die Resorption von Kalzium, sodass nur eine kombinierte Gabe von Vitamin D und Kalzium in der Lage ist, den postoperativen Kalziumabfall zu mitigieren oder ganz zu verhindern. Schlussfolgerung Eine Arbeitsanweisung (SOP) zur Diagnostik und Therapie der postoperativen Hypokalzämie sollte in jeder Klinik etabliert werden. Ein entsprechender Entwurf wurde in die Arbeit aufgenommen, damit Diagnose- und Therapiepfad effektiv an lokale Gegebenheiten angepasst werden können.
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Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

Article in Thieme eJournals:
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Recurrent vestibulopathy: are cVEMP, oVEMP and inner ear MRI useful to distinguish patients with Menière's disease and vestibular migraine?

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Eur Arch Otorhinolaryngol. 2021 Mar 2. doi: 10.1007/s00405-021-06716-6. Online ahead of print.

ABSTRACT

PURPOSE: The aim of this study was to assess the rate of endolymphatic hydrops (EH) on MRI and the rate of otolithic dysfunction with cVEMP and oVEMP, in patients with recurrent vertigo such as Menière's disease (MD), vestibular migraine (VM) and vestibular Menière's disease (vMD).

METHODS: In this retrospective study, we performed 3D-FLAIR sequences with delayed acquisition in 20 MD, 20 VM and 20 vMD patients. Each subject was then assessed for the presence of EH on MRI. All patients underwent pure-tone audiometry, cVEMP and oVEMP.

RESULTS: In MD patients, EH was observed in 18 (90%) out of 20 patients while EH was observed in only 1 MV (5%) and 1 vMD (5%) patients. We found significant differences between groups for the presence of EH on MRI (p = 0.001). MD patients had significant higher PTA level (p < 0.001) and oVEMP impairment than MV and vMD (p = 0.08 and p = 0.06, respectively). However, no significant differences were observed for cVEMP impairment, either asymmetric ratio (p = 0.36) and 1000/500 ratio (p = 0.20).

CONCLUSIONS: Concerning cVEMP, we observed no significant differences between VM, vMD and MD. However, we observed higher oVEMP impairment, PTA level and EH on MRI in MD patients. We believe that MRI could be used to differentiate MD from VM patients with cochlear symptoms. However, in cases of migraine associated with recurrent vertigo and without cochlear symptoms, we believe that MRI is not a useful tool to differentiate between VM and vMD.

PMID:33651151 | DOI:10.1007/s00405-021-06716-6

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Reply to: Letter to the editor regarding 'Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society' by Piazza et al

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Eur Arch Otorhinolaryngol. 2021 Mar 1. doi: 10.1007/s00405-021-06715-7. Online ahead of print.

NO ABSTRACT

PMID:33649868 | DOI:10.1007/s00405-021-06715-7

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A simple method for olfactory rehabilitation following total laryngectomy

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Eur Arch Otorhinolaryngol. 2021 Mar 2. doi: 10.1007/s00405-021-06711-x. Online ahead of print.

ABSTRACT

PURPOSE: The aim of the study is to demonstrate the effectiveness of spraying odor particles using sinus rinse kits for olfactory rehabilitation in patients with total laryngectomy.

METHODS: Olfactory rehabilitation was performed by applying four different odorant particles orthonasally using a sinus rinse kit pump for 30 min each day for a duration of 6 months. Olfactory function was evaluated by performing olfactory tests before the rehabilitation and at sixth month after the rehabilitation process.

RESULTS: The average CCCRC score prior to olfactory rehabilitation was 2.28 ± 0.79 (between 1.50 and 3.75), while it was 4.46 ± 0.5 (between 3.50 and 5.25) out of a maximum score of 7 after 6 months of olfactory rehabilitation (p value < 0.0001) CONCLUSION: Our results suggest that the use of sinus rinse kits is very si mple, inexpensive, easy-to-use, and effective in providing passive olfaction to patients requiring olfactory rehabilitation.

PMID:33651149 | DOI:10.1007/s00405-021-06711-x

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Thoracoscopic total laryngo-pharyngo-oesophagectomy for the pharyngoesophageal junction cancer: a single-center experience of multidisciplinary team

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Eur Arch Otorhinolaryngol. 2021 Mar 2. doi: 10.1007/s00405-021-06706-8. Online ahead of print.

ABSTRACT

PURPOSE: The aims of this study were to review the surgical experience and evaluate the feasibility of thoracoscopic total laryngo-pharyngo-oesophagectomy by multidisciplinary team in the patients with pharyngoesophageal junction cancer.

METHODS: A total of 31 patients with pharyngoesophageal junction cancer who underwent thoracoscopic total laryngo-pharyngo-oesophagectomy with gastric pull-up reconstruction performed by a collaborative thoracic surgery and otolaryngology surgery team in our department from January 2009 to January 2019 were retrospectively analysed. Surgical experience, Postoperative morbidity, overall survival were evaluated.

RESULTS: The median age was 62 years old. Among these patients, 20 had hypopharyngeal cancer, 11 had cervical oesophageal cancer. No patients died during the perioperative period, a nd the median operation time was 4 h 30 min. The mean hospital stay was 13 days. The rate of complications was 32.3%. There were two cases of anastomotic leakage, four cases of moderate pulmonary infection. The median follow-up period was 31 months. Four patients were lost to follow-up in the second and fourth years and were considered to have died at that time. The 3- and 5-year overall survival rates were 52.6% and 31.6%, respectively.

CONCLUSION: As a salvage surgery, thoracoscopic total laryngo-pharyngo-oesophagectomy by multidisciplinary team can be performed with an acceptable level of perioperative morbidity and mortality, relatively good recovery, and acceptable survival outcome for patients with pharyngoesophageal junction cancer.

PMID:33651150 | DOI:10.1007/s00405-021-06706-8

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Planning tools and indications for 'virtual surgery' for the Bonebridge bone conduction system

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HNO. 2021 Mar 2. doi: 10.1007/s00106-020-00976-0. Online ahead of print.

ABSTRACT

BACKGROUND: Implantation of the Bonebridge (MED-EL, Innsbruck, Austria), an active semi-implantable transcutaneous bone conduction hearing system, involves the risk of impression or a lesion in intracranial structures, such as the dura or sigmoid sinus. Therefore, determining the optimal implant position requires careful preoperative radiological planning.

OBJECTIVE: The aim of this study was to provide an overview of the possibilities for preoperative radiological planning for the Bonebridge implantation and to evaluate their indications and feasibility.

MATERIALS AND METHODS: A systematic literature search was conducted in the PubMed/MEDLINE database for all studies with preoperative planning or implant placement as the primary endpoint or that secondarily mention preoperative planning.

RESULTS: Of 558 studies, 49 fulfilled the inclusion criteria. In 18 studies, preoperative planning and floating mass transducer (FMT) placement were the primary endpoints, whereas in 31 studies, preoperative planning was described secondarily.

CONCLUSION: There are both freely available and commercial tools involving different time commitments for preoperative three-dimensional (3D) planning and intraoperative transfer. Preoperative 3D planning can increase the safety of Bonebridge implantation.

PMID:33651113 | DOI:10.1007/s00106-020-00976-0

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