Δευτέρα 1 Οκτωβρίου 2018
More than keratitis, ichthyosis, and deafness: multisystem effects of lethal GJB2 mutations
Infant death in KID syndrome is recognized; its association with specific genotypes and pathophysiology is inadequately understood.
Lower Socioeconomic Status is Associated with Delayed Access to Care for Infantile Hemangioma, a Cohort Study
What is already known on this topic: Children with Medicaid face greater barriers of access-to-care. Delayed management of complicated infantile hemangiomas compromises outcomes. What this article adds to our knowledge. Lower socioeconomic status is associated with delayed care for infantile hemangioma, but not among children with institutional care-management services. How this information impacts clinical practice and/or changes patient care. Institution-facilitated managed-care programs may moderate socioeconomic disparities in accessing timely specialty care and improve outcomes.
Overall and Subgroup Prevalence of Acne Vulgaris Among Patients with Hidradenitis Suppurativa
This analysis augments the significantly literature establishing the link between acne vulgaris and hidradenitis suppurativa. Understanding the burden of acne vulgaris among patients with hidradenitis suppurativa may support evaluation and optimization of management for both conditions.
Association between atopic dermatitis and autoimmune disorders in US adults and children: A cross-sectional study
•The present study found increased risk of autoimmune disorders of the skin, endocrine, gastrointestinal, hematologic and musculoskeletal systems in both adults and children, with a predilection for females, young age, Asian race/ethnicity and those without asthma.•Clinicians should consider increased screening for autoimmune disorders in atopic dermatitis patients.
Cost Analysis of a Store and Forward Teledermatology Consult System in Philadelphia
When conducted appropriately, store and forward teledermatology can be cost saving by reducing unnecessary office-based dermatology clinic and emergency room visits. With engagement of stakeholders and proper planning, patients can obtain improved access to high-quality sustainable dermatologic care, in the setting of teledermatology reimbursement.
Guideline-Based Medicine Grading based upon the Guidelines of Care for Ambulatory Atopic Dermatitis Treatment in the United States
Although atopic dermatitis practice guidelines are published, how doctors adhere to these guidelines is unknown. Using a grading system analogous to the United States A to F system, healthcare providers receive a grade of B or C in their atopic dermatitis management, suggesting that physicians may benefit from reviewing guidelines of care
A systematic review and meta-analysis of the regional and age-related differences of atopic dermatitis clinical characteristics
•This study identified considerable heterogeneity of atopic dermatitis, with seventy eight different signs and symptoms identified, and notable differences by study region and age-group.•These phenotypical differences should be incorporated into the diagnosis and severity assessment of atopic dermatitis patients.
"Treatment of male pattern alopecia with platelet-rich plasma: a double blind controlled study with analysis of platelet number and growth factor levels"
Platelet rich plasma (PRP) has shown promise for androgenetic alopecia. We found PRP injections significantly increased hair growth compared to placebo, but response was not correlated with platelet or the measured growth factors in PRP
Opioid Prescribing for Acute Postoperative Pain After Cutaneous Surgery
Nonopioid interventions should be used for patients in pain; patients who need opioids should also receive nonopioid therapy. Among patients requiring opioids, 36-hour supply is generally adequate. Requests for refill beyond expected duration of need should require return visit.
Infertility and Teratogenicity after Paternal Exposure to Systemic Dermatologic Medications: A Systematic Review
Many systemic dermatologic medications can cause teratogenicity after maternal exposure. Some of these medications can cause infertility and may have teratogenic effects after paternal exposure; however, teratogenicity is understudied. Information on fertility effects or teratogenicity risk should guide discussions with male patients using these medications and looking to conceive.
The role of TERT promoter mutations in differentiating recurrent nevi from recurrent melanomas: a retrospective, case-control study
Repigmentation at previous biopsy sites pose a significant diagnostic dilemma given clinical and histologic similarities between recurrent nevi and locally recurrent melanoma. While common in melanoma, the role of TERT promoter mutations (TPMs) in recurrent nevi is unknown.
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A Case of Diprosopus Tetraophthalmos: Ocular Findings and Surgical Treatment of Exposure KeratopathyDiprosopus is a rare variation of conjoined twinning. In this report, ophthalmic findings in an infant with diprosopus tetraophthalmos are p...
