Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis

xlomafota13 shared this article with you from Inoreader Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):206-214. doi: 10.14639/0392-100X-N1379. NO ABSTRACT PMID:34264913 | DOI:10.14639/0392-100X-N1379 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Applications of intraoperative angiography in head and neck reconstruction

xlomafota13 shared this article with you from Inoreader Applications of intraoperative angiography in head and neck reconstruction Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):215-220. doi: 10.14639/0392-100X-N1161. ABSTRACT OBJECTIVE: Laser-assisted angiography with indocyanine green (LAIG) allows objective intraoperative evaluation of tissue vascularity. We endeavored to describe our experience with this technique in the head and neck region. METHODS: A retrospective review from February 2016 till October 2018 was conducted. We included patients who underwent head and neck procedures in which LAIG was employed. The main outcome was postoperative wound complications. We analysed the influence of LAIG results in intraoperative decision-making process. RESULTS: Nineteen patients were included, and follow-up was for at least 6 months. LAIG was employed in 11 local flaps, 9 free flaps and 6 cases of pharyngeal closure during total laryngectomies. Wound complications occurred in two cases with distal tip flap necrosis. LAIG findings resulted in changes in decision making intraoperatively in 84% of procedures, which consisted in trimming poorly perfused tissues. There were no pharyngocutaneous fistulas. CONCLUSIONS: This represents a descriptive report on the use of LAIG on diverse head and neck reconstruction cases, with important impact on the decision-making process. A low number of postoperative wound complications were observed. PMID:34264914 | DOI:10.14639/0392-100X-N1161 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Less common forms of posterior canal benign paroxysmal positional vertigo

xlomafota13 shared this article with you from Inoreader Less common forms of posterior canal benign paroxysmal positional vertigo Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):255-262. doi: 10.14639/0392-100X-N1032. NO ABSTRACT PMID:34264919 | DOI: 10.14639/0392-100X-N1032 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Persistent postural perceptual dizziness following paroxysmal positional vertigo in migraine

xlomafota13 shared this article with you from Inoreader Persistent postural perceptual dizziness following paroxysmal positional vertigo in migraine Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):263-269. doi: 10.14639/0392-100X-N1017. ABSTRACT OBJECTIVE: This prospective study aimed to investigate the role of migraine in favouring the onset of persistent postural perceptual dizziness (PPPD) following paroxysmal positional vertigo (PPV). METHODS: A group of patients who came to our attention suffering of PPV with or without migraine and/or vestibular migraine (VM) was examined. Three months after the resolution, an ana mnestic research was conducted aimed at establishing whether any patient-related dizziness could meet the diagnostic criteria for PPPD. RESULTS: 12 of the 240 patients recruited met the diagnostic criteria for PPPD for an overall incidence of 5%, with 3 (1.85%) belonging to the non-migraine group and 9 (11.5%) to the migraine group. In the latter, 6 (28.6%) patients with VM and 3 (5.26%) without VM were affected. CONCLUSIONS: The study shows a significant increase of PPPD diagnosis in migraine compared to patients without migraine (p = 0.003). Within migraine there was a significant increase in those with VM compared to patients without VM (p = 0.0016). No difference emerged between patients without migraine and migraine patients without VM (p > 0.05). The presence of VM in patient's history, but not migraine without VM, appears to significantly increase the incidence of PPPD in patients with PPV. PMID:34264920 | DOI:10.14639/0392-100X-N1017 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Application of a symptoms score questionnaire after conjunctivodacryocystorhinostomy: outcomes

xlomafota13 shared this article with you from Inoreader Application of a symptoms score questionnaire after conjunctivodacryocystorhinostomy: outcomes Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):248-254. doi: 10.14639/0392-100X-N0881. ABSTRACT OBJECTIVE: To evaluate medium/long term outcomes and patient satisfaction through relief of symptoms and improved quality of life (QoL) after Jones tube conjunctivodacryocystorhinostomy (JT-CDCR) using the Naso Lacrimal Duct Obstruction symptom-score (NLDO-SS). METHODS: We conducted a retrospective, non-comparative, multicentric study including patients with complete obstruction of the superior and inferior proximal lacrimal drainage system. All patients underwent JT-CDCR, and the patency of the tube was evaluated with saline irrigation and endoscopic examination. We assessed patient satisfaction and quality of life administering the NLDO-SS. RESULTS: We enrolled 16 patients, for a total of 21 eyes operated. The success rate for procedures was 81%. The success rate for single parameters was globally 95.9%; if considered separately, ocular symptoms and nasal symptoms were respectively 94.3% and 100%. CONCLUSIONS: JT-CDCR was a reliable procedure, able to solve symptoms in a majority of patients and guaranteed a good quality of life over a long period of time. PMID:34264918 | DOI:10.14639/0392-100X-N0881 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Pseudo-spontaneous nystagmus increases Bow and Lean Test accuracy

xlomafota13 shared this article with you from Inoreader Pseudo-spontaneous nystagmus increases Bow and Lean Test accuracy Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):270-276. doi: 10.14639/0392-100X-N1136. ABSTRACT OBJECT: The aim of this study was to evaluate the effectiveness of the Bow and Lean Test (BLT) based on nystagmus intensity and direction evaluation (NID-BLT) in the diagnosis of benign paroxysmal positional vertigo of the lateral semicircular canal (LSC-BPPV). We hypothesised that the presence of a pseudo-spontaneous nystagmus increases the diagnostic accuracy of the test. METH ODS: The BLT was performed in 32 subjects affected by LSC-BPPV. RESULTS: BLT was positive in 27 cases with a sensitivity of 84.3% and an accuracy of 70.4%. In other words, it was possible to carry out a BPPV root canal diagnosis (LSC) with BLT in 27 patients, of whom 19 also received a diagnosis of side and form. Pseudo-spontaneous nystagmus was detected in 15 patients, all of whom were BLT positive. In these patients, a clear diagnosis of form and side was also obtained in 14 cases (accuracy 93.3%). In the 12 patients without pseudo-spontaneous nystagmus and BLT positive, a diagnosis of side and form was reached in 5 cases (accuracy 41.6%). The comparison between percentages (Chi square test) showed a significant difference (p = 0.038). CONCLUSIONS: The presence of a pseudo-spontaneous nystagmus, as an expression of more mobile debris within the canal or a more deflectable cupula, increases the accuracy of the BLT. PMID:34264921 | DOI:10.14639/0392-100X-N1136 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

N3 (> 6 cm) squamous cell carcinoma of the head and neck: outcomes and predictive factors in 104 patients

xlomafota13 shared this article with you from Inoreader N3 (> 6 cm) squamous cell carcinoma of the head and neck: outcomes and predictive factors in 104 patients Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):221-229. doi: 10.14639/0392-100X-N1437. ABSTRACT OBJECTIVE: To report outcome and predictive factors in patients with N3 (> 6 cm) non-metastatic locally advanced head and neck squamous cell carcinoma (LAHNSCC) treated with a conservative approach or with initial surgery. METHODS: 104 patients were included: 69 treated with radiotherapy (RT) ± chemotherapy (CT) and 35 with nodal surgery with or without primary tumour resect ion, which was completed in 30 patients by adjuvant RT ± CT. Positron-emission tomography-computed tomography (PET-CT) guided surveillance after RT ± CT was standard. RESULTS: Two-year overall survival (OS) and locoregional control (LRC) were 39.4% and 37.5%, respectively. In univariate analysis, body mass index (BMI), performance status (PS), p16 status and haemoglobin value influenced OS and disease-free survival (DFS). In multivariate analysis, p16 positive status and BMI ≥ 25 remained independent prognostic factors for better OS (p = 0.023) and DFS (p = 0.002). Only under/normal weight remained an independent and adverse significant prognostic factor in multivariate analysis for regional control (RC). Patients treated with primary RT ± CT had slightly better 2-year OS (43.5% versus 33.3%, p = 0.31). CONCLUSIONS: Patients with N3 LAHNSCC have poor prognosis, but long term LRC is achievable, especially in overweight patients and those with a good PS. PMID:34264915 | DOI:10.14639/0392-100X-N1437 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cross-cultural adaptation and Italian validation of chronic otitis media outcome test 15 (COMOT-15)

xlomafota13 shared this article with you from Inoreader Cross-cultural adaptation and Italian validation of chronic otitis media outcome test 15 (COMOT-15) Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):277-281. doi: 10.14639/0392-100X-N1184. ABSTRACT OBJECTIVE: Chronic suppurative otitis media (CSOM) may result in a serious impairment of the quality of life (QoL). The most relevant characteristics of CSOM are well represented in the "Chronic Otitis Media Outcome Test 15" questionnaire (COMOT-15). The aim of the study was to translate and adapt the COMOT-15 questionnaire into Italian. METHODS: This is a prospective study cond ucted on 52 Caucasian Italian-speaking patients with CSOM and 52 controls. The linguistic adaptation of the COMOT-15 consisted of the translation of the English version into Italian and reliability assessment of the translation. Psychometric measurements included internal consistency and test-retest reliability. RESULTS: Cronbach's α was 0.95. The test-retest reliability showed a strong positive correlation for total score and all subscales. Age and gender had no influence on the scores. The correlation between the COMOT-15 and the pure tone average showed a significant association for the scale "Hearing Function". CONCLUSIONS: The Italian COMOT-15 questionnaire provides good internal consistency and is suitable for QoL evaluation in Italian-speaking patients suffering from CSOM. In addition, it is able to evaluate the subjective symptoms perceived by patients. PMID:34264922 | DOI:10.14639/0392-100X-N1184 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Transmeatal microsurgery for intralabyrinthine and intrameatal schwannomas: literature review

xlomafota13 shared this article with you from Inoreader Transmeatal microsurgery for intralabyrinthine and intrameatal schwannomas: literature review Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):282-284. doi: 10.14639/0392-100X-N1443. NO ABSTRACT PMID:34264923 | DOI: 10.14639/0392-100X-N1443 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Predictive factors for recurrence of papillary thyroid carcinoma: analysis of 4,085 patients

xlomafota13 shared this article with you from Inoreader Predictive factors for recurrence of papillary thyroid carcinoma: analysis of 4,085 patients Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Jun;41(3):236-242. doi: 10.14639/0392-100X-N1412. ABSTRACT OBJECTIVE: The incidence of papillary thyroid carcinoma (PTC) has increased in recent years and its treatment remains controversial. The objective of this study is to identify clinicopathological predictive factors of tumour recurrence. METHODS: We retrospectively analysed 4,085 patients who underwent thyroidectomy for PTC from 1996 to 2015. Patients were stratified according to American Thyroid Association (ATA) risk categories and clinicopathological features were evaluated to identify independent factors for recurrence. RESULTS: After a mean follow-up of 58.7 (range 3-256.5) months, tumour recurrence was diagnosed in 176 (4.3%) patients, mostly in lymph nodes. Distant metastasis occurred in 18 patients (0.4%). There were 3 (0.1%) cancer-related deaths. Multivariate analysis showed that tumour size >10 mm, multifocality, extrathyroidal extension and lymph node metastasis (all, P < 0.001) were independent risk factors for recurrence. Further, recurrence was identified in 1.6% of the ATA low-risk, 7.4% of the intermediate-risk and 22.7% of the high-risk patients (P < 0.001). CONCLUSIONS: In PTC patients, tumour size >10 mm, multifocality, extrathyroidal extension and presence of lymph node metastasis as well as the ATA recurrence staging system effectively predict recurrence. PMID:34264917 | DOI:10.14639/0392-100X-N1412 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Three dimensional printed models of the airway for preoperative planning of open Laryngotracheal surgery in children: Surgeon’s perception of utility

xlomafota13 shared this article with you from Inoreader Three dimensional printed models of the airway for preoperative planning of open Laryngotracheal surgery in children: Surgeon's perception of utility Via Journal of Otolaryngology - Head & Neck Surgery Preoperative planning of open laryngotracheal surgery is important for achieving good results. This study examines the surgeon's perception of the importance of using life size 3D printed models of the pediatr... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.