Mycoses, EarlyView.
Δευτέρα 16 Απριλίου 2018
Natural UV‐Screening Mechanisms of Norway Spruce (Picea abies [L.] Karst.) Needles
Photochemistry and Photobiology, EarlyView.
Concordance of somatic mutational profile in multiple primary melanomas
Pigment Cell &Melanoma Research, EarlyView.
Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology
Pigment Cell &Melanoma Research, EarlyView.
Curcumin accelerates cutaneous wound healing via multiple biological actions: The involvement of TNF‐α, MMP‐9, α‐SMA, and collagen
International Wound Journal, EarlyView.
Hearing aids in patients with vestibular schwannoma: Interest of the auditory brainstem responses
Clinical Otolaryngology, EarlyView.
Long‐lasting allergic contact dermatitis caused by methylisothiazolinone in wall paint: A case report
Contact Dermatitis, EarlyView.
Acute generalized exanthematous pustulosis induced by oxacillin confirmed by patch testing
Contact Dermatitis, EarlyView.
Drug reaction with eosinophilia and systemic symptoms syndrome induced by benznidazole
Contact Dermatitis, EarlyView.
Allergic contact dermatitis caused by isobornyl acrylate in OmniPod, an innovative tubeless insulin pump
Contact Dermatitis, EarlyView.
Successful treatment with interleukin‐17A antagonists of generalized pustular psoriasis in patients without IL36RN mutations
The Journal of Dermatology, EarlyView.
Dacryocystitis mimicking erysipelas due to a giant dacryolith
The Journal of Dermatology, EarlyView.
Pediatric case of generalized pustular psoriasis developing acute pancreatitis
The Journal of Dermatology, EarlyView.
Linear immunoglobulin A bullous dermatosis limited to oral mucosa associated with ulcerative colitis
The Journal of Dermatology, EarlyView.
Efficacy and toxicity of ipilimumab used after nivolumab in patients with melanoma
The Journal of Dermatology, EarlyView.
Pilomatricoma with bullous‐like/anetodermic appearance: Possibly associated with matrix metalloproteinases
The Journal of Dermatology, Volume 45, Issue 4, Page 505-506, April 2018.
Expression of aurora kinase A expression in dermatofibrosarcoma protuberans
The Journal of Dermatology, Volume 45, Issue 4, Page 507-508, April 2018.
High‐intensity focused ultrasound treatment after cryolipolysis may be used to reduce pain: Two case report
Dermatologic Therapy, EarlyView.
Exploring the combination of SSKI and topical heparin in a case of erythema nodosum migrans
Dermatologic Therapy, EarlyView.
Radiotherapy in the management of classic Kaposi's sarcoma: A single institution experience from Northeast Turkey
Dermatologic Therapy, EarlyView.
Two cases of large cell acanthoma successfully treated with photodynamic therapy
Dermatologic Therapy, EarlyView.
Secukinumab: A positive outcome in a patient with severe psoriasis and HBV‐HCV co‐infection
Dermatologic Therapy, EarlyView.
Merkel cell carcinoma in a patient treated with infliximab: Beware of the subcutaneous nodule
Australasian Journal of Dermatology, EarlyView.
Clinical features and repair options for nonmelanoma skin cancers of the eyebrow
Australasian Journal of Dermatology, EarlyView.
A retrospective clinico‐pathological study comparing lichen planus pigmentosus with ashy dermatosis
Australasian Journal of Dermatology, EarlyView.
Lymphocytic thrombophilic arteritis complicated by systemic involvement
Australasian Journal of Dermatology, EarlyView.
Hyperglycaemia is inversely correlated with live M. bovis BCG‐specific CD4+ T cell responses in Tanzanian adults with latent or active tuberculosis
Immunity, Inflammation and Disease, EarlyView.
Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse
Immunity, Inflammation and Disease, EarlyView.
Effect of the S‐nitrosoglutathione reductase inhibitor N6022 on bronchial hyperreactivity in asthma
Immunity, Inflammation and Disease, EarlyView.
Cutis tricolor parvimaculata in ring chromosome 15 syndrome: A case report
Pediatric Dermatology, EarlyView.
Bibbidi bobbidi bald: Two “hairowing” tales of Princess Package hairstyles
Pediatric Dermatology, EarlyView.
Atypical aluminium patch tests in children with persistent itching postvaccinal nodules
Pediatric Dermatology, EarlyView.
Pyoderma gangrenosum in an infant: A case report and review of the literature
Pediatric Dermatology, EarlyView.
Chromhidrosis due to exogenous oxidizing heavy metals: Clinical and laboratory findings
Pediatric Dermatology, EarlyView.
Treatment of acrodermatitis continua of Hallopeau with ustekinumab as monotherapy after failure of anti‐TNF agents
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
ÖGDV Preisträger stellen sich vor: Der Wissenschaftspreis der ÖGDV 2017 ging an Dr. rer. nat. Stefan Hainzl und Dr. rer. nat. Patricia Peking aus Salzburg
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 527-528, April 2018.
Der subkutan gestielte retroaurikuläre Insellappen zur Rekonstruktion von Defekten des Cavum conchae
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 508-510, April 2018.
Journal‐Club
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 526-526, April 2018.
In Memoriam Prof. Dr. Ludwig Suter 1938–2018
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 535-536, April 2018.
3rd Science Days of the Austrian Society of Dermatology and Venereology – ÖGDV Forschungstage
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 532-533, April 2018.
ÖGDV Preisträger stellen sich vor: Der Österreichische Dermatologenpreis – Unilever Preis 2017 ging an Dr. Thomas Kocher aus Salzburg
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 529-531, April 2018.
Perichondritis am Ohr eines afghanischen Immigranten
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 500-503, April 2018.
Schmerzhafte gruppierte erythematöse Papeln in segmentaler Anordnung
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 496-499, April 2018.
Vernarbende Alopezien
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 435-463, April 2018.
Nicht IgE‐vermittelte Hypersensitivität auf Macrogol 6000
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 478-480, April 2018.
S1‐Leitlinie – Dermatosen bei dermaler Lymphostase
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 512-524, April 2018.
Tattooentfernung mit Laser: Gibt es bereits Pikosekundenlaser?
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 467-469, April 2018.
Die Wirksamkeit einer neuen Nagelspange für die Behandlung von eingewachsenen Nägeln
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 417-425, April 2018.
Kutanes Pseudolymphom nach quadrivalenter HPV‐Impfung – eine seltene Nebenwirkung
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 465-467, April 2018.
Patient satisfaction in 1,827 patients following various methods of facial reconstruction based on age, defect size and site
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 426-433, April 2018.
Anuläres paraneoplastisches bullöses Pemphigoid imitiert lineare IgA‐Dermatose bei einem 40‐jährigen Patienten
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 481-483, April 2018.
S1 Guidelines – Dermatoses associated with dermal lymphostasis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 512-523, April 2018.
Multibazilläre Lepra mit dem Erscheinungsbild einer Sinusitis und eines chronischen, persistierenden Angioödems
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 470-472, April 2018.
Cicatricial alopecia
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 16, Issue 4, Page 435-461, April 2018.
In vivo reflectance confocal microscopy combined with the ‘spaghetti technique’ for the identification of surgical margins of lentigo maligna: experience in 70 patients
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Generalized pustular psoriasis: a review and update on treatment
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Who will treat inflammatory skin diseases in the year 2020?
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Oral psoriasis and SIBO: is there a link?
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Circular RNA expression profile analysis of severe acne by RNA‐Seq and bioinformatics
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Google search trends in psoriasis: a pilot evaluation of global population interests
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Efficacy of suplatast tosilate in a case of recurrent eosinophilic annular erythema
International Journal of Dermatology, EarlyView.
Lichen striatus following scarlet fever in a 3‐year‐old female patient
International Journal of Dermatology, EarlyView.
Granulocyte colony‐stimulating factor‐producing melanoma treated with the combination of dabrafenib and trametinib
International Journal of Dermatology, EarlyView.
Vedolizumab‐induced acne in inflammatory bowel disease
International Journal of Dermatology, EarlyView.
Concentric targetoid scaly plaques in a patient with severe rheumatoid arthritis
International Journal of Dermatology, EarlyView.
Heavily pigmented fibroepithelioma of Pinkus mimicking melanoma
International Journal of Dermatology, EarlyView.
Gray‐bluish cutaneous pigmentation and ice‐pick scars induced by vandetanib therapy
International Journal of Dermatology, EarlyView.
Transient improvement of skin symptoms in an adult patient with pediatric‐onset cutaneous mastocytosis treated with interferon‐α
International Journal of Dermatology, EarlyView.
A review of bullous pemphigoid associated with PD‐1 and PD‐L1 inhibitors
International Journal of Dermatology, EarlyView.
Issue Information
International Journal of Dermatology, Volume 57, Issue 5, Page i-iii,503-504, May 2018.
Teaching & Learning Tips 7: small‐group discussion
International Journal of Dermatology, Volume 57, Issue 5, Page 583-586, May 2018.
A case of pigmentary mosaicism associated with diploid/triploid mixoploidy
International Journal of Dermatology, EarlyView.
Religious stigmata: a dermato‐psychiatric approach and differential diagnosis
International Journal of Dermatology, EarlyView.
Novel use of combination therapeutic plasma exchange and rituximab in the treatment of nivolumab‐induced bullous pemphigoid
International Journal of Dermatology, EarlyView.
Mohs micrographic surgery for basal cell carcinoma of the scrotum
International Journal of Dermatology, EarlyView.
Skin ultrasound is a useful tool for evaluating and monitoring eosinophilic fasciitis
International Journal of Dermatology, EarlyView.
Is pleasure all that is good about experience?
Abstract
Experientialist accounts of wellbeing are those accounts of wellbeing that subscribe to the experience requirement. Typically, these accounts are hedonistic. In this article I present the claim that hedonism is not the most plausible experientialist account of wellbeing. The value of experience should not be understood as being limited to pleasure, and as such, the most plausible experientialist account of wellbeing is pluralistic, not hedonistic. In support of this claim, I argue first that pleasure should not be understood as a broad term to describe valuable experiences generally. I then analyze responses to the main argument against a monistic view on the value of experience: the philosophy of swine objection. I argue that such responses deviate from the central hedonistic view that only pleasure and pain matter for wellbeing. I then argue that the argument can be avoided on a pluralistic account, and formulate a plausible candidate for an account of pluralistic experientialism, in which, besides pleasure, non-hedonic aspects of experience like novelty, compassion, and aesthetic value also contribute to wellbeing.
Algebraic structuralism
Abstract
This essay is about how the notion of "structure" in ontic structuralism might be made precise. More specifically, my aim is to make precise the idea that the structure of the world is (somehow) given by the relations inhering in the world, in such a way that the relations are ontologically prior to their relata. The central claim is the following: one can do so by giving due attention to the relationships that hold between those relations, by making use of certain notions from algebraic logic.
Determination of optimal ultrasound planes for the initialisation of image registration during endoscopic ultrasound-guided procedures
Abstract
Purpose
Navigation of endoscopic ultrasound (EUS)-guided procedures of the upper gastrointestinal (GI) system can be technically challenging due to the small fields-of-view of ultrasound and optical devices, as well as the anatomical variability and limited number of orienting landmarks during navigation. Co-registration of an EUS device and a pre-procedure 3D image can enhance the ability to navigate. However, the fidelity of this contextual information depends on the accuracy of registration. The purpose of this study was to develop and test the feasibility of a simulation-based planning method for pre-selecting patient-specific EUS-visible anatomical landmark locations to maximise the accuracy and robustness of a feature-based multimodality registration method.
Methods
A registration approach was adopted in which landmarks are registered to anatomical structures segmented from the pre-procedure volume. The predicted target registration errors (TREs) of EUS-CT registration were estimated using simulated visible anatomical landmarks and a Monte Carlo simulation of landmark localisation error. The optimal planes were selected based on the 90th percentile of TREs, which provide a robust and more accurate EUS-CT registration initialisation. The method was evaluated by comparing the accuracy and robustness of registrations initialised using optimised planes versus non-optimised planes using manually segmented CT images and simulated ( \(n=9\) ) or retrospective clinical ( \(n=1\) ) EUS landmarks.
Results
The results show a lower 90th percentile TRE when registration is initialised using the optimised planes compared with a non-optimised initialisation approach (p value \(< 0.01\) ).
Conclusions
The proposed simulation-based method to find optimised EUS planes and landmarks for EUS-guided procedures may have the potential to improve registration accuracy. Further work will investigate applying the technique in a clinical setting.
Quinazoline clubbed 1,3,5-triazine derivatives as VEGFR2 kinase inhibitors: design, synthesis, docking, in vitro cytotoxicity and in ovo antiangiogenic activity
Abstract
A series of quinazoline clubbed 1,3,5-triazine derivatives (QCT) were synthesized and evaluated for their in vitro anticancer activity against HeLa (human cervical cancer), MCF-7 (human breast cancer cell), HL-60 (human promyelocytic leukemia cell), HepG2 (human Hepatocellular carcinoma cell), and one normal cell line HFF (human foreskin fibroblasts). In vitro assay result encouraged to further move towards in ovo anticancer evaluation using chick embryo. The series of QCT derivatives showed higher anticancer and antiangiogenic activity against HeLa and MCF-7 cell lines. In the series, synthetic molecule 8d, 8l, and 8m displayed significant activity. Further, these results substantiated by docking study on VGFR2. SAR study concluded that the potency of drugs depends on the nature of aliphatic substitution and the heterocyclic ring system.
Graphical Abstract
In vivo estimation of target registration errors during augmented reality laparoscopic surgery
Abstract
Purpose
Successful use of augmented reality for laparoscopic surgery requires that the surgeon has a thorough understanding of the likely accuracy of any overlay. Whilst the accuracy of such systems can be estimated in the laboratory, it is difficult to extend such methods to the in vivo clinical setting. Herein we describe a novel method that enables the surgeon to estimate in vivo errors during use. We show that the method enables quantitative evaluation of in vivo data gathered with the SmartLiver image guidance system.
Methods
The SmartLiver system utilises an intuitive display to enable the surgeon to compare the positions of landmarks visible in both a projected model and in the live video stream. From this the surgeon can estimate the system accuracy when using the system to locate subsurface targets not visible in the live video. Visible landmarks may be either point or line features. We test the validity of the algorithm using an anatomically representative liver phantom, applying simulated perturbations to achieve clinically realistic overlay errors. We then apply the algorithm to in vivo data.
Results
The phantom results show that using projected errors of surface features provides a reliable predictor of subsurface target registration error for a representative human liver shape. Applying the algorithm to in vivo data gathered with the SmartLiver image-guided surgery system shows that the system is capable of accuracies around 12 mm; however, achieving this reliably remains a significant challenge.
Conclusion
We present an in vivo quantitative evaluation of the SmartLiver image-guided surgery system, together with a validation of the evaluation algorithm. This is the first quantitative in vivo analysis of an augmented reality system for laparoscopic surgery.
Fiducial-based fusion of 3D dental models with magnetic resonance imaging
Abstract
Purpose
Magnetic resonance imaging (MRI) is widely used in study of maxillofacial structures. While MRI is the modality of choice for soft tissues, it fails to capture hard tissues such as bone and teeth. Virtual dental models, acquired by optical 3D scanners, are becoming more accessible for dental practice and are starting to replace the conventional dental impressions. The goal of this research is to fuse the high-resolution 3D dental models with MRI to enhance the value of imaging for applications where detailed analysis of maxillofacial structures are needed such as patient examination, surgical planning, and modeling.
Methods
A subject-specific dental attachment was digitally designed and 3D printed based on the subject's face width and dental anatomy. The attachment contained 19 semi-ellipsoidal concavities in predetermined positions where oil-based ellipsoidal fiducial markers were later placed. The MRI was acquired while the subject bit on the dental attachment. The spatial position of the center of mass of each fiducial in the resultant MR Image was calculated by averaging its voxels' spatial coordinates. The rigid transformation to fuse dental models to MRI was calculated based on the least squares mapping of corresponding fiducials and solved via singular-value decomposition.
Results
The target registration error (TRE) of the proposed fusion process, calculated in a leave-one-fiducial-out fashion, was estimated at 0.49 mm. The results suggest that 6–9 fiducials suffice to achieve a TRE of equal to half the MRI voxel size.
Conclusion
Ellipsoidal oil-based fiducials produce distinguishable intensities in MRI and can be used as registration fiducials. The achieved accuracy of the proposed approach is sufficient to leverage the merged 3D dental models with the MRI data for a finer analysis of the maxillofacial structures where complete geometry models are needed.
Enhanced TiO 2 nanorods photocatalysts with partially reduced graphene oxide for degrading aqueous hazardous pollutants
Abstract
Enhanced TiO2 nanorods (TNRs) with partially reduced graphene oxide (RGO) (designated as GT) were prepared for degrading aqueous hazardous pollutants. The degree of RGO oxidation had an important role in affecting the photoelectronic and photocatalytic activities of GT composites. The study examined the impact of the degree of RGO oxidation on the photocatalytic activities. The photocatalytic activity of the materials was investigated for degrading rhodamine b (RhB), methyl orange (MO), methylene blue (MB), and phenol by using ultraviolet (UV) light. The highest photocatalytic activity was observed when the atomic oxygen-to-carbon (O/C) ratio of RGO was 0.130 ± 0.003. This study suggested the photocatalytic performance was maximized by preserving a selected amount of the RGO oxygen-containing groups. The work reported in this study on optimizing the RGO-based TiO2 photocatalyst could serve as a promising approach for preparing and optimizing other types of carbon-based photocatalysts such as graphene-based CdS.
Κυριακή 15 Απριλίου 2018
Upgradation of chemical, fuel, thermal, and structural properties of rice husk through microwave-assisted hydrothermal carbonization
Abstract
The process parameters of microwave hydrothermal carbonization (MHTC) have significant effect on yield of hydrochar. This study discusses the effect of process parameters on hydrochar yield produced from MHTC of rice husk. Results revealed that, over the ranges tested, a lower temperature, lower reaction time, lower biomass to water ratio, and higher particle size produce more hydrochar. Maximum hydrochar yield of 62.8% was obtained at 1000 W, 220 °C, and 5 min. The higher heating value (HHV) was improved significantly from 6.80 MJ/kg of rice husk to 16.10 MJ/kg of hydrochar. Elemental analysis results showed that the carbon content increased and oxygen content decreased in hydrochar from 25.9 to 47.2% and 68.5 to 47.0%, respectively, improving the energy and combustion properties. SEM analysis exhibited modification in structure of rice husk and improvement in porosity after MHTC, which was further confirmed from BET surface analysis. The BET surface area increased from 25.0656 m2/g (rice husk) to 92.6832 m2/g (hydrochar). Thermal stability of hydrochar was improved from 340 °C for rice husk to 370 °C for hydrochar.
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A Case of Diprosopus Tetraophthalmos: Ocular Findings and Surgical Treatment of Exposure KeratopathyDiprosopus is a rare variation of conjoined twinning. In this report, ophthalmic findings in an infant with diprosopus tetraophthalmos are p...
