FDG PET/CT in Eosinophilic Solid and Cystic Renal Cell Carcinoma With Lung Metastases

alexandrossfakianakis shared this article with you from Inoreader FDG PET/CT in Eosinophilic Solid and Cystic Renal Cell Carcinoma With Lung Metastases via Clinical Nuclear Medicine - Published Ahead-of-Print Eosinophilic solid and cystic renal cell carcinoma is a recently described emerging renal tumor. Usefulness of FDG PET/CT in the management of eosinophilic solid and cystic renal cell carcinoma has been rarely reported. We describe FDG PET/CT findings in a case of eosinophilic solid and cystic renal cell carcinoma with lung metastases. The primary renal tumor and its metastases showed intense FDG uptake with SUVmax of 29.3 for the primary tumor and 21 for the lung metastases. View on Web

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Prostate Cancer With Solitary Bone Metastasis in the Mandible

alexandrossfakianakis shared this article with you from Inoreader Prostate Cancer With Solitary Bone Metastasis in the Mandible via Clinical Nuclear Medicine - Published Ahead-of-Print A 79-year-old man with prostate cancer found to have a solitary bone lesion in the mandible on initial staging bone scan. The sclerotic lesion had a sunburst appearance on CT. As biopsy was nondiagnostic, the patient underwent segmental mandibulectomy. Postoperative pathology results confirmed as metastasis from prostate cancer. View on Web

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68Ga-FAPI-04 PET/CT in Epithelioid Hemangioendothelioma With Pleura and Bone Metastases

alexandrossfakianakis shared this article with you from Inoreader 68Ga-FAPI-04 PET/CT in Epithelioid Hemangioendothelioma With Pleura and Bone Metastases via Clinical Nuclear Medicine - Published Ahead-of-Print Epithelioid hemangioendothelioma is a low- to intermediate-grade malignant vascular tumor with a slowly progressive course and unpredictable prognosis. We report a case of epithelioid hemangioendothelioma with pleura and bone metastases on 68Ga-FAPI-04 PET/CT in a 65-year-old woman who underwent surgery and chemotherapy. View on Web

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Solitary Splenic Metastasis From Endometrial Carcinoma Revealed on FDG PET/CT

alexandrossfakianakis shared this article with you from Inoreader Solitary Splenic Metastasis From Endometrial Carcinoma Revealed on FDG PET/CT via Clinical Nuclear Medicine - Published Ahead-of-Print Solitary splenic metastasis from endometrial carcinoma is rare. We report a case of imaging findings of solitary splenic metastasis in a 53-year-old woman who underwent resection surgery of endometrial carcinoma of uterus 1 year ago. On FDG PET/CT, it presented as a solitary soft tissue mass with an SUVmax of 18.44. The postoperative pathology supported metastasis from endometrial carcinoma. View on Web

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Hypermetabolic Esophagitis Dessicans Superficialis Mimicking Esophageal Cancer on FDG PET/CT

alexandrossfakianakis shared this article with you from Inoreader Hypermetabolic Esophagitis Dessicans Superficialis Mimicking Esophageal Cancer on FDG PET/CT via Clinical Nuclear Medicine - Published Ahead-of-Print An 83-year-old man with history of multiple myeloma obtained an FDG PET/CT for surveillance. Although there was no evidence of metabolically active myeloma, an incidental highly FDG-avid focus was noted at the gastroesophageal junction. Findings were interpreted as malignancy. The patient underwent esophagogastroduodenoscopy, which showed nonerythematous desquamation of the distal esophagus consistent with esophagitis dessicans superficialis (EDS) without any evidence of malignancy. There is paucity of literature regarding EDS and its image findings. This case illustrates an instance of focal mass-like uptake on FDG PET/CT, which represents an endoscopy- and pathology-confirmed EDS and mimics esophageal cancer. View on Web

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Adherence Of Candida Albicans to Five Long‐Term Silicone‐Based Denture Lining Materials Bonded to CAD‐CAM Denture Base

alexandrossfakianakis shared this article with you from Inoreader Adherence Of Candida Albicans to Five Long‐Term Silicone‐Based Denture Lining Materials Bonded to CAD‐CAM Denture Base via Journal of Prosthodontics Abstract Purpose : Knowledge about quantifying the number as well as the retention and adhesion of Candida albicans blastoconidia to silicone denture liners is limited. Thus, the aim of this in vitro study was to explore the adherence of Candida albicans to the surface of five long-term silicone-based soft denture lining materials, using artificial saliva. Materials & Methods A total of 50 specimens (10 × 10 × 3 mm) of five long-term resilient liners (Molloplast-B; GC Reline Soft; Elite Soft Relining; Tokuyama Sofreliner S; Ufigel SC), bonded to a computer-aided design and computer-aided manufacturing denture base, were prepared. The specimens were inoculated and incubated in artificial saliva for 1h and 24h with a standardized (2.8 × 106 cfu/ml) Candida albicans suspension. At the end of the incubation period, the specimens were stained with acridine orange and observed, using fluorescence microscopy. Results : After 1h and in 24h, Molloplast B demonstrated significantly earlier adherence of Candida albicans cells compared to the other chairside materials (p<0.001 and p<0.001, respectively), where the mean number of cells also increased in the frontal parts. Regarding the rate of Candida albicans proliferation from 1h to 24 hours within the materials, there was an increase in all materials (Molloplast B: p<0.001; GC Reline Soft: p = 0.220; Elite Soft Relining: p = 0.032; Tokuyama Sofreliner S: p = 0.001; Ufigel Sc: p = 0.001). The Ufigel Sc showed a significant 2.5-fold increase at 24h. Conclusions : Long-term silicone denture liners accumulate a significant amount of Candida albicans blastoconidia and their coverage by them increases progressively over time. This article is protected by copyright. All rights reserved View on Web

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Melanin-Targeted PET Imaging Sheds Light on Pigment Epithelioma in Corpus Ciliare

alexandrossfakianakis shared this article with you from Inoreader Melanin-Targeted PET Imaging Sheds Light on Pigment Epithelioma in Corpus Ciliare via Clinical Nuclear Medicine - Published Ahead-of-Print A 57-year-old woman had gradually decreased visual acuity in the left eye, accompanied by distension and pain. MRI demonstrated a small neoplasm in corpus ciliare, which promoted PET imaging for further assessment. 18F-FDG PET imaging found no obvious uptake in the lesion. However, melanin-targeted PET imaging demonstrated the lesion with avid 18F-PFPN (18F-N-(2-diethylaminoethyl)-4-(2-[2-ethoxy]-ethoxy)pyridine) accumulation (SUVmax, 7.1), which suggested it with melanin expression. Pigmented epithelial adenoma was further confirmed by pathology. Our case illustrated that pigmented epithelial adenoma is characterized by av id 18F-PFPN accumulations and can be detected even in a hidden location with a size of ≤5 mm. View on Web

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Flexural Strength of Various Provisional Restorative Materials for Rehabilitation After Aging

alexandrossfakianakis shared this article with you from Inoreader Flexural Strength of Various Provisional Restorative Materials for Rehabilitation After Aging via Journal of Prosthodontics Abstract Purpose Durability of provisional restoration is crucial for full-mouth reconstruction, which may be influenced by aging. This study evaluated the effect of aging on the flexural strength of provisional materials for oral rehabilitation. Materials and Methods Bar specimens (2×2×25 mm) were fabricated from CAD-CAM [Vita CAD-Temp® (VC), Telio®CAD (TC), artBloc® (RC)], auto polymerized- [Protemp™IV (PA), Luxatemp® (LA), Unifast™Trad (UA)]. Results TCNG indicated the highest mean of σ (133.49 ±4.32), whereas VCNG indicated the lowest mean of σ (84.62 ±3.73) for non-aging. Upon aging process, TCAG revealed the highest mean of σ (123.11 ±4.55), while VCAG possessed the lowest mean of σ (84.05 ±6.39). Significant differences among various provisional materials were indicated (p = 0.001). Aging significantly affected flexural strength (p = 0.001). Conclusions The CAD-CAM provisional material possessed higher flexural strength than heat-polymerized PMMA and auto-polymerized PMMA, which was suggested as a provisional material for rehabilitation. Aging reduced strength for all materials tested. This article is protected by copyright. All rights reserved View on Web

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Development and validation of the Fat Attitudes Assessment Toolkit (FAAT): A multidimensional nonstigmatizing measure of contemporary attitudes toward fatness and fat people

alexandrossfakianakis shared this article with you from Inoreader Development and validation of the Fat Attitudes Assessment Toolkit (FAAT): A multidimensional nonstigmatizing measure of contemporary attitudes toward fatness and fat people via Journal of Applied Social Psychology Abstract Many instruments recommended for measuring attitudes toward fatness and "obesity" were developed in the 1990s, a time when the "obesity epidemic" was gaining momentum and anti-fat rhetoric was normative. Consequently, these instruments have tended to focus on assessing negative appraisals of fatness and fat people and reinforce weight stigma. As fat discourse has matured and expanded to incorporate fat positive attitudes, a nonstigmatizing way of measuring contemporary fat attitudes and beliefs in quantitative research is required. To address this need, we developed the Fat Attitudes Assessment Toolkit (FAAT). In this article, we describe the development of the FAAT and provide initial evidence for the scale's validity and psychometric properties across three studies. Study 1 included a systematic process for developing the extensive item pool that was reviewed by subject matter experts and a community panel. We explored and identified an initial multidimensional structure for the FAAT. Study 2 expanded and confirmed the factor structure with additional analyses in an independent sample and provided evidence for the overall reliability of the subscale scores and reliability as a function of gender and identification as fat. Construct and criterion validity of the subscale scores were also demonstrated. Study 3 provided evidence for the test-retest reliability of the FAAT subscales scores over time. The FAAT includes nine robust scales: Empathy, Activism Orientation, Size Acceptance, Attractiveness, Critical Health, General Complexity, Socioeconomic Complexity, Responsibility, and Body Acceptance. Specific subscales can be combined to form two composite measures: Fat Acceptance and Attribution Complexity. The scales that comprise the FAAT measure specific elements of attitudes towards fat people that are frequently targeted in weight stigma reduction research and activism; the FAAT thus offers a powerful and precise method for evaluating weight stigma reduction interventions that allows for an assessment of shifts toward more positive attitudes. View on Web

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SARS-CoV-2 incidence and risk factors in a national, community-based prospective cohort of U.S. adults

alexandrossfakianakis shared this article with you from Inoreader SARS-CoV-2 incidence and risk factors in a national, community-based prospective cohort of U.S. adults via Clinical Infectious Diseases Advance Access Abstract Background Prospective cohort studies of SARS-CoV-2 incidence complement case-based surveillance and cross-sectional seroprevalence surveys. Methods We estimated the incidence of SARS-CoV-2 infection in a national cohort of 6,738 U.S. adults, enrolled March-August 2020. Using Poisson models, we examined the association of social distancing and a composite epidemiologic risk score with seroconversion. The risk score was created using LASSO regression to identify factors predictive of seroconversion. The selected factors were household crowding, confirmed case in household, indoor dining, gathering with groups ≥ 10, and no masking in gyms/salons. Results Among 4,510 individuals with ≥1 serologic test, 323 (7.3%, 95% confidence interval [CI] 6.5%-8.1%) seroconverted by January 2021. Among 3,422 participants seronegative in May-September 2020 and retested during November 2020-January 2021, 161 seroconverted over 1,646 person-years of follow-up (9.8 per 100 person-years [95%CI 8.3-11.5]). Seroincidence rate was lower among females compared to males (IRR: 0.69, 95% CI 0.50-0.94) and higher among Hispanic (IRR: 2.09, 95% CI 1.41-3.05) participants compared to White non-Hispanic. In adjusted models, participants who reported social distancing with people they did not know (IRRalways vs. never: 0.42, 95% CI 0.20-1.0) and with people they knew (IRRalways vs. never 0.64, 95%CI 0.39-1.06; IRRsometimes vs. never 0.60, 95% CI 0.38-0.96) had lower seroconversion risk. Seroconversion risk increased with epidemiologic risk score (IRRmedium vs. low 1.68, 95% CI 1.03-2.81; IRRhigh vs. low 3.49, 95% CI 2.26-5.58). Only 29% of those who seroconverted reported isolating and 19% were asked about contacts. Conclusion Modifiable risk factors and poor reach of public health strategies drove SARS-CoV-2 transmission across the U.S. View on Web

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