Acta Histochemica,

Effects of short and long-term alcohol-based fixation on Sprague-Dawley rat tissue morphology, protein and nucleic acid preservation

Publication date: Available online 3 July 2019Source: Acta HistochemicaAuthor(s): Simona Panzacchi, Federica Gnudi, Daniele Mandrioli, Rita Montella, Valentina Strollo, Bruce Alexander Merrick, Fiorella Belpoggi, Eva TibaldiAbstractSafety concerns on the toxic and carcinogenic effects of formalin exposure have drawn increasing attention to the search for alternative low risk fixatives for processing tissue specimens in laboratories worldwide. Alcohol-based fixatives are considered some of the most...

Acta Histochemica

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 The Journal of Pathology,

Cold atmospheric plasma modulates endothelial nitric oxide synthase signalling and enhances burn wound neovascularisation

Abstract Treatment with cold atmospheric plasma (CAP) has been reported to promote wound healing in animals. However, how this process is mediated remains unclear. In this study we examined the mechanisms which underlie the improved wound healing effects of CAP, and examine the roles of associated reactive oxygen and nitrogen species (RONS), which are generated by plasma. By using in vitro models which mimicked various steps of angiogenesis, we demonstrated that CAP triggered the production of nitric...

The Journal of Pathology

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