Psoriasis is an immune-mediated disease with a genetic basis, associated with an inappropriate immune activation, mediated by T cells. There is predominance of the TH1 response and, more recently, was confirmed the participation of TH17 cells. Some studies have shown a direct relationship between psoriasis (Ps) and geographic tongue (GT), both with etiologic, histopathologic and genetic similarities. The aim of this study was to demonstrate that the histologic pattern and immunoreactivity to anti–IL-6, –IL-17, and –IL-23 antibodies, in the inflammatory response of geographic tongue are similar to psoriasis.
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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Παρασκευή 3 Αυγούστου 2018
TH17 pathway assessment in the inflammatory infiltrate of psoriasis and geographic tongue
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Publication date: Available online 28 September 2017 Source: Actas Dermo-Sifiliográficas Author(s): F.J. Navarro-Triviño
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