Multiple granular cell tumors associated with joint hypermobility, facial dysmorphism, and asymptomatic neurologic findings: A rare syndrome

Background: The granular cell tumor (GCT), also known as Abrikossoff tumor, is a rare, benign tumor. Its supposed origin is related to Schwann cells. It generally presents with a solitary nodule, but multiple tumors may be found in up to 25% of patients, less frequently in children. Bakos and Muscardin have reported multiple GCT associated with malformations in cardiovascular, neurologic and musculoskeletal systems in addition to a dysmorphic face, which could be features of a rare syndrome.