Atypical Fibroxanthoma: Systematic Review and Meta-analysis of Treatment with Mohs Micrographic Surgery or Excision

The two treatment modalities most commonly used for AFX are wide local excision (WLE) and Mohs micrographic surgery (MMS). Mohs micrographic surgery (MMS) is associated with a lower local recurrence rate than WLE. MMS should be considered for treatment of AFX, especially in anatomically sensitive areas and in immunosuppressed patients.