Sinecatechins ointment 10% (Veregen®) for genital warts: percutaneous penetration of Epigallocatechin Gallate concentrations in the stratum corneum collected by adhesive tape stripping method

Abstract

Camellia sinensis extract/Sinecatechins/10% ointment is a registered topical therapy for the treatment of external and perianal genital warts, to be applied thrice daily. Pharmacokinetic studies elucidating the most optimal frequency of application have not been undertaken, and a less frequent (more convenient) application schedule might also be effective. Here, we measured epigallocatechin gallate (EGCG) concentrations, the main Camellia sinensis extract component, in the stratum corneum (SC) over time after one application.

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