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Δευτέρα 8 Μαρτίου 2021

Good's syndrome with a relapsed bloodstream infection induced by Alcaligenes sp. after thymectomy: A case report

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Exp Ther Med. 2021 Apr;21(4):399. doi: 10.3892/etm.2021.9830. Epub 2021 Feb 24.

ABSTRACT

Good's syndrome (GS) or thymoma-associated immunodeficiency is a rare clinical syndrome with poor prognosis. The varied and unspecified clinical manifestations of GS commonly lead to a missed or delayed diagnosis. Thus, misdiagnosis and missed diagnosis are common. The present case study reports on a patient who suffered from a relapsed bloodstream infection caused by Alcaligenes sp. 6 months after thymectomy. The patient was finally diagnosed with GS after analyzing the clinical features and detecting T-lymphocyte subsets in the peripheral blood and humoral immune function. The patient's condition improved after anti-infection treatment and supplementation with intravenous immunoglobulin. Furthermore, no infection was observed during the 1-year follow-up.

PMID:33680121 | PMC:PMC7918125 | DOI:10.3892/etm.2021.9830

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