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Δευτέρα 26 Οκτωβρίου 2020

[Primary extra-axial chondroid chordoma of the anterior nasal septum: case report of a rare chordoma with literature review].

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[Primary extra-axial chondroid chordoma of the anterior nasal septum: case report of a rare chordoma with literature review].

HNO. 2020 Oct 23;:

Authors: Holley C, Breining T, Scheithauer M, Möller P, Barth TFE

Abstract
An 87-year-old patient reported a nodular, progressively enlarging mass of the anterior nasal septum leading to partial obstruction of the nostrils. The tumor showed no infiltration of the subcutis, bone, or paranasal sinuses in imaging or intraoperatively. Histological examination revealed a chondroid tumor with lobular growth and physaliferous cell morphology. Immunohistochemistry revealed a brachyury-positive tumor without EWSR1 rearrangement, leading to the diagnosis of a chondroid chordoma. The reported case demonstrates the differential diagnostic considerations pertaining to this rare tumor, which can also have an untypical and very rare extra-axial location. Review of the literature identified 34 primary extraosseous chordomas of the nose, nasopharynx, and paranasal sinuses, and allowed the nasal chordoma presented herein to be included in this group of extra-axial chordomas.

PMID: 33095325 [PubMed - as supplied by publisher]

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