Treatment of an ulcerated hemangioma with dehydrated human amnion/chorion membrane allograft

We report the case of a 10-month-old girl with a large segmental "beard-distributed" infantile hemangioma (IH) with recalcitrant ulceration, successfully treated with dehydrated Human Amnion/Chorion Membrane allograft (dHACM, EpiFix; MiMedx Group, Marietta, GA). The patient initially presented at 10 days of life with respiratory distress and was noted to have a segmental IH of the lower face and neck. Endoscopy confirmed involvement of the upper airway. Findings from a PHACE (posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, eye abnormalities, sternal cleft, and supraumbilical raphe) workup were normal.