Idiopathic localized involutional lipoatrophy in a child with spontaneous resolution

Reena Kumari Sharma, Mudita Gupta, Anuj Sharma

Indian Journal of Paediatric Dermatology 2018 19(4):366-368

Idiopathic localized involutional lipoatrophy (ILIL) is focal loss of subcutaneous tissue without any clinical or histopathological inflammation. Histopathology of ILIL characteristically shows diminutive fat lobules composed of small adipocyte resembling embryonic fat tissue. Immunohistochemical examination reveals a number of CD-68 positive macrophages in the fat lobules. Most reported cases of ILIL were unilateral in young women; we are reporting a case of 4-year-old child with bilateral involvement showing quick spontaneous resolution.