Secondary localized cutaneous amyloidosis in mycosis fungoides

Secondary localized cutaneous amyloidosis is often not clinically apparent, but may be seen histologically. It is associated with several skin tumors, and has been reported with PUVA use. To date, there are three reported cases of secondary localized cutaneous amyloidosis associated with mycosis fungoides before any treatment. We present a case of a 39-year-old woman who presented to the dermatology clinic for evaluation of facial acne. During the exam, several 5-10 mm hypopigmented patches were noted on the bilateral ventral forearms.