Objectives: Increased levels of blood d-dimers (D-D), the by-products of fibrin degradation, are linked to the severity of chronic spontaneous urticaria (CSU) and to poor response to antihistamines H1 (AH1). Omalizumab (OMA) is a human monoclonal anti–immunoglobulin E antibody registered as an add-on treatment of CSU in adults and adolescents (≥12 years old) with insufficient response to AH1. The SUNRISE study assessed the efficacy of Omalizumab on CSU symptoms and the correlation between D-D levels and response over time to treatment with OMA to explore its potential predictive value.
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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Τρίτη 14 Αυγούστου 2018
Correlation of d-dimers to response to treatment in chronic spontaneous urticaria (UAS7 score): Results from the SUNRISE study
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Publication date: Available online 28 September 2017 Source: Actas Dermo-Sifiliográficas Author(s): F.J. Navarro-Triviño
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