Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: real-world data from a nationwide cohort study in Taiwan.

Prior studies have shown that methotrexate may lead to liver cirrhosis in psoriatic patients. Real-world data show that long-term methotrexate use is not associated with an increased risk of liver cirrhosis among psoriatic patients with chronic viral hepatitis. Methotrexate may be a treatment option in psoriatic patients with chronic viral hepatitis.