Morphea: current concepts of skin and systemic manifestations

Publication date: Available online 10 April 2018
Source:Clinics in Dermatology
Author(s): Stephanie Florez-Pollack, Elaine Kunzler, Heidi T. Jacobe
Morphea is an inflammatory, sclerosing skin disorder that can involve the underlying soft tissues. Although the cause of morphea remains poorly investigated, genetic predisposition, immune dysregulation, and environmental factors have been implicated. Morphea is associated with cosmetic and functional sequelae, while internal organ involvement is rare. Early diagnosis and treatment are imperative to minimize damage such as limitation of range of motion. This review summarizes advances in diagnosis and treatment of morphea, allowing clinicians to better serve patients with this condition.