Stabilization of Microtubules Restores Barrier Function after Cytokine-induced Defects in Reconstructed Human Epidermis

A variety of human skin disorders is characterized by defects in the epidermal barrier, leading to dehydration, itchiness, and rashes. Previously published literature suggests that microtubule stabilization at the cortex of differentiating keratinocytes is necessary for the formation of the epidermal barrier.