Amniotic Band Syndrome: A Review of 2 Cases

Amniotic band syndrome is a rare congenital disorder caused by entrapment of fetal parts (usually a limb or digits) in fibrous amniotic bands while in utero that presents with complex multisystem anomalies. The authors report 2 children with amniotic band syndrome who presented to the ophthalmic unit of the authors' pediatric hospital. One of them presented with telecanthus, syndactyly, amputated toes, and unilateral epiphora diagnosed as congenital nasolacrimal duct obstruction. She was managed conservatively with lacrimal sac massage and provided with refractive correction while she simultaneously underwent multiple surgeries for correction of clubfoot and craniosynostosis. The second patient presented with cleft lip, cleft palate, multiple constriction bands in upper limbs and fingers with unilateral microphthalmos, microcornea, typical iris coloboma, and retinochoroidal coloboma, very similar to a case reported in literature. These 2 cases provide an overview of the clinical spectrum of ophthalmic manifestations along with their staged optimum rehabilitation. Accepted for publication February 6, 2018. Consent for photographs: Obtained and archived from the parents of the patients for printing identifiable photographs of their children. The authors have no financial or conflicts of interest to disclose. Address correspondence and reprint requests to Zia Chaudhuri, M.S., F.R.C.S. (Glasg), F.I.C.O., Department of Ophthalmology, Lady Hardinge Medical College, University of Delhi, PGIMER, Dr RML Hospital, New Delhi, India. E-mail: ziachaudhuri2@gmail.com © 2018 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.