Sustained remission of recalcitrant cutaneous lymphoid hyperplasia after thalidomide treatment

Cutaneous lymphoid hyperplasia (CLH) is a benign lymphoid infiltrate thought to represent an exaggerated response to antigenic stimulation.1-3 Treatment includes trigger avoidance and both pharmacologic and surgical modalities.3 We present a case of recalcitrant CLH with durable clinical regression after treatment with thalidomide.