Skin Burn Associated With Photochemotherapy

Objective psoralen and ultraviolet A (PUVA) phototherapy (PT) has become a standard treatment for several severe skin diseases. Photosensitization is done by oral psoralen intake. In minor cases, PUVA can lead to skin changes like erythema and hyperpigmentation. However, it can also lead to severe burn injuries when exposed to extensive UV light. This makes the treatment in a burn center inevitable. Methods We report the clinical observation of a 38-year-old man presenting with an extensive burn injury caused by sun tanning after PUVA PT. Conclusions There are just few cases of extensive burns induced by PUVA PT. Prevention becomes manifest in patient information, correct calculation of dosage, evaluation of photosensitivity, and close observation. In cases of severe burn injuries, patients should be referred to a burn center for optimal conservative treatment. Surgical intervention is usually not necessary.