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Πέμπτη 28 Σεπτεμβρίου 2017

52 words for snow: Dermatologists naming epidermal nevi

Abstract

In the April 2017 issue of BJD, Kuentz et al (1) report an FGFR2 mutation in a subtype of nevus sebaceus (NS). On review of the histopathology, we question the clinical diagnosis and feel that these cases may better fit with keratinocytic epidermal nevus (KEN) or remain unclassified "epidermal nevi". Both KEN and NS are papillomatous with epidermal hyperplasia (2), and while the authors note "small foci of sebaceous glands and immature hair follicle buds", they wisely observe that the early gestational age may have limited the full adnexal development and thus, it is possible these may have developed into other clinical subtypes of epidermal nevi.

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